Search results
Results from the WOW.Com Content Network
Topical nicotinamide and topical zinc are safe, however, there are no FDA pregnancy category ratings. [27] [28] Topical salicylic acid and topical dapsone are classified as FDA pregnancy category C. [23] [28] Acne medications to avoid during pregnancy include oral isotretinoin and topical tazarotene as there have been reports of birth defects.
The pregnancy category of a medication is an assessment of the risk of fetal injury due to the pharmaceutical, if it is used as directed by the mother during pregnancy. It does not include any risks conferred by pharmaceutical agents or their metabolites in breast milk. Every drug has specific information listed in its product literature.
Serious side effects may include low blood pressure or heart attack. [10] Whether use is safe during pregnancy or breastfeeding is unclear. [2] [10] When used by people with liver problems, and in elderly individuals, doses should be reduced. [10] Amlodipine works partly by vasodilation (relaxing the arteries and increasing their diameter). [10]
For other side effects, data are inconclusive: A study comparing lercanidipine to first-generation drugs found no difference in the frequency of headache and flush, [7] but switching from amlodipine, felodipine or nitrendipine (all at least second generation) to lercanidipine significantly decreased side effects in another study. [5]
Common side effects include diarrhea and abdominal pain. [11] It is in pregnancy category X, meaning that it is known to result in negative outcomes for the fetus if taken during pregnancy. [11] In rare cases, uterine rupture may occur. [11] It is a prostaglandin analogue—specifically, a synthetic prostaglandin E 1 (PGE 1). [11]
A Food and Drug Administration meeting that opened Monday comes more than two years after the agency declared the drug ineffective and called for its removal. Drugmaker Covis Pharma has challenged ...
Midodrine is a prodrug which forms the active metabolite, desglymidodrine, which is an α 1-adrenergic receptor agonist and exerts its actions via activation of α 1-adrenergic receptors of the arteriolar and venous vasculature, producing an increase in vascular tone and elevation of blood pressure.
WASHINGTON (AP) — The maker of the only U.S. drug intended to prevent premature births is making a last-ditch effort […] The post FDA pushes to remove pregnancy drug, company pushes back ...