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Pages in category "CYP1A2 inhibitors" The following 15 pages are in this category, out of 15 total. This list may not reflect recent changes. A. Aciclovir ...
Following is a table of selected substrates, inducers and inhibitors of CYP1A2. Inhibitors of CYP1A2 can be classified by their potency, such as: Strong inhibitor being one that causes at least a 5-fold increase in the plasma AUC values of sensitive substrates metabolized through CYP1A2, or more than 80% decrease in clearance thereof. [18]
"INHIBITORS, INDUCERS AND SUBSTRATES OF CYTOCHROME P450 ISOZYMES". "The Life Raft Group: Long List of Inhibitors and Inducers of CYP3A4 and CYP2D6". "DRUGBANK Online: Cytochrome P-450 Enzyme Inhibitors". "MEDICATIONS METABOLIZED BY CYTOCHROME P450 3A4" (PDF)
Clozapine, imipramine, paracetamol, phenacetin Heterocyclic aryl amines Inducible and CYP1A2 5-10% deficient oxidize uroporphyrinogen to uroporphyrin (CYP1A2) in heme metabolism, but they may have additional undiscovered endogenous substrates. are inducible by some polycyclic hydrocarbons, some of which are found in cigarette smoke and charred ...
Anti-interleukin-6 agents are a class of therapeutics.Interleukin 6 is a cytokine relevant to many inflammatory diseases and many cancers. [1] Hence, anti-IL6 agents have been sought.
"Hearst Magazines and Yahoo may earn commission or revenue on some items through these links." “Acute inflammation helps to protect and heal our bodies, however, chronic inflammation is a ...
Cimetidine is a potent inhibitor of certain cytochrome P450 (CYP) enzymes, [20] [32] including CYP1A2, CYP2C9, CYP2C19, CYP2D6, CYP2E1, and CYP3A4. [20] [32] [33] The drug appears to primarily inhibit CYP1A2, CYP2D6, and CYP3A4, [34] of which it is described as a moderate inhibitor. [8]
Both brand name Lexapro and generic escitalopram are considered SSRIs, or selective serotonin reuptake inhibitors, a class of medications commonly used to treat major depressive disorder, anxiety ...