Search results
Results from the WOW.Com Content Network
Benzo[a]pyrene (BaP or B[a]P) is a polycyclic aromatic hydrocarbon and the result of incomplete combustion of organic matter at temperatures between 300 °C (572 °F) and 600 °C (1,112 °F). The ubiquitous compound can be found in coal tar, tobacco smoke and many foods, especially grilled meats.
Chemical structure of benzo[a]pyrene Chemical structure of benzo[e]pyrene. A benzopyrene is an organic compound with the formula C 20 H 12.Structurally speaking, the colorless isomers of benzopyrene are pentacyclic hydrocarbons and are fusion products of pyrene and a phenylene group.
Benzopyrene is a derivative in which a fifth benzene ring has been fused to the pyrene system, and is a component of tobacco smoke which is a procarcinogen partly responsible for the carcinogenic and mutagenic effects of smoking. [1] Benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide is a metabolite of benzo[a]pyrene formed by the introduction of ...
TCDD may in some conditions potentiate the carcinogenic effects of other compounds. An example is benzo(a)pyrene that is metabolized in two steps, oxidation and conjugation. Oxidation produces epoxide carcinogens that are rapidly detoxified by conjugation, but some molecules may escape to the nucleus of the cell and bind to DNA causing a ...
Pyrene is a polycyclic aromatic hydrocarbon (PAH) consisting of four fused benzene rings, resulting in a flat aromatic system. The chemical formula is C 16 H 10. This yellow-green solid is the smallest peri-fused PAH (one where the rings are fused through more than one face). Pyrene forms during incomplete combustion of organic compounds. [10]
A metabolite of benzo[]pyrene forms an intercalated DNA adduct, at center. In molecular genetics, a DNA adduct is a segment of DNA bound to a cancer-causing chemical.This process could lead to the development of cancerous cells, or carcinogenesis.
AOL Mail welcomes Verizon customers to our safe and delightful email experience!
Benzo(a)pyrene (BaP) is a well-known PAH and carcinogen which is often found in exhaust fumes and cigarette smoke. [201] PAHs have been reported to administer their toxic effects through oxidative stress by increasing the production of Reactive Oxygen Species (ROS) which can result in inflammation and cell death.