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Notoedric mange, also referred to as Feline scabies, is a highly contagious skin infestation caused by an ectoparasitic and skin burrowing mite Notoedres cati (Acarina, Sarcoptidae). N. cati is primarily a parasite of felids , but it can also infest rodents , lagomorphs , and occasionally also dogs and foxes.
Ivermectin is an antiparasitic drug. [7] After its discovery in 1975, [8] its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. [9] Approved for human use in 1987, [10] it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis.
Mange (/ ˈ m eɪ n dʒ /) is a type of skin disease caused by parasitic mites. [1] Because various species of mites also infect plants, birds and reptiles, the term "mange", or colloquially "the mange", suggesting poor condition of the skin and fur due to the infection, is sometimes reserved for pathological mite-infestation of nonhuman mammals.
Oral ivermectin (while not FDA approved specifically for scabies treatment) deserves consideration as it has shown to be a more practical and effective treatment. Dosage is based on body weight ...
Selamectin, sold under the brand name Revolution, among others, is a topical parasiticide and anthelminthic used on dogs and cats. [2] It treats and prevents infections of heartworms, fleas, ear mites, sarcoptic mange (scabies), and certain types of ticks in dogs, and prevents heartworms, fleas, ear mites, hookworms, and roundworms in cats.
A study has demonstrated that scabies is markedly reduced in populations taking ivermectin regularly; [51] the drug is widely used for treating scabies and other parasitic diseases, particularly among the poor and disadvantaged in the tropics, beginning with the developer Merck providing the drug at no cost to treat onchocerciasis from 1987.
Benzyl benzoate is an effective and inexpensive topical treatment for human scabies. [7] It has vasodilating and spasmolytic effects and is present in many asthma and whooping cough drugs. [ 8 ] It is also used as an excipient in some testosterone -replacement medications (like Nebido ) for treating hypogonadism .
Ivermectin is the drug of choice for treatment, due to its low side effect profile. [24] Albendazole is also effective in treating strongyloidiasis. Mebendazole has a much higher failure rate in clinical practice than albendazole or ivermectin. [25] However, these drugs have little effect on the autoinfective larvae.
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