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A latex fixation test, also called a latex agglutination assay or test (LA assay or test), is an assay used clinically in the identification and typing of many important microorganisms. These tests use the patient's antigen - antibody immune response.
The mononuclear spot test or monospot test, a form of the heterophile antibody test, [1] is a rapid test for infectious mononucleosis due to Epstein–Barr virus (EBV). It is an improvement on the Paul–Bunnell test. [2] The test is specific for heterophile antibodies produced by the human immune system in response to EBV
Others such as Shigella (and E. coli) and Salmonella are traditionally detected using a slide agglutination test. [6] [8] HLA types are originally determined with the complement fixation test. [9] Newer procedures include the latex fixation test and various other immunoassays.
Rapid diagnostic test (RDT) (dipstick and cassette), latex agglutination Early morning urine Tests in community settings without laboratories, which are disease-specific include tests for Chagas disease , cholera , COVID-19 , diabetes mellitus , hepatitis B and C, HIV , influenza , malaria, Streptococcal pharyngitis, sickling disorders ...
Agglutination is the clumping of particles. The word agglutination comes from the Latin agglutinare (glueing to). Agglutination is a reaction in which particles (as red blood cells or bacteria) suspended in a liquid collect into clumps usually as a response to a specific antibody.
The Weil–Felix test is an agglutination test for the diagnosis of rickettsial infections. It was first described in 1916. By virtue of its long history and of its simplicity, it has been one of the most widely employed tests for rickettsia on a global scale, despite being superseded in many settings by more sensitive and specific diagnostic tests.
Nontreponemal tests are screening tests, very rapid and relatively simple, but need to be confirmed by treponemal tests. [1] Centers for Disease Control and Prevention (CDC)-approved standard tests include the VDRL test (a slide test), the rapid plasma reagin (RPR) test (a card test), the unheated serum reagin (USR) test, and the toluidine red ...
A slide coagulase test is run with a negative control to rule out autoagglutination. Two drops of saline are put onto the slide labeled with sample number, Test (T) and control (C). The two saline drops are emulsified with the test organism using a wire loop, straight wire, or wooden stick.