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Spina bifida (SB; /ˌspaɪnə ˈbɪfɪdə/, [9] Latin for 'split spine') [10] is a birth defect in which there is incomplete closing of the spine and the membranes around the spinal cord during early development in pregnancy. [1] There are three main types: spina bifida occulta, meningocele and myelomeningocele. [1]
Congenital heart defects, hydronephrosis, omphalocele and meningocele (spina bifida) are also common. Cystic hygromas occur but are uncommon. [citation needed] Triploid fetuses have intrauterine growth restriction beginning early in the pregnancy, as early as 12 weeks, and does not affect the head as severely as the body.
The gene that encodes the human HES7 protein is 5kb long and is found on chromosome 17, on the short arm at position 13.1. [8] from base pair 8,120,590 to 8,126,032. In mice, HES7 is located on chromosome 11. [9] HES7 has 62 known orthologues. [10] The HES7 gene is expressed in the presomitic mesoderm [9] where expression fluctuates in two hour ...
Spina bifida occulta means hidden split spine. [20] In this type of neural tube defect, the meninges do not herniate through the opening in the spinal canal. [ 19 ] The most frequently seen form of spina bifida occulta is when parts of the bones of the spine, called the spinous process , and the neural arch appear abnormal on a radiogram ...
Spina bifida is characterized by a midline cleft in the vertebral arch. It usually causes no symptoms in dogs. It usually causes no symptoms in dogs. It is seen most commonly in Bulldogs and Manx cats. [ 5 ]
Spina bifida is a birth defect that affects the lowest part of the spine and occurs when a fetus's neural tube does not fully close, causing the backbone that protects the spinal cord not to form ...
Grainyhead-like genes are a family of highly conserved transcription factors that are functionally and structurally homologous across a large number of vertebrate and invertebrate species. For an estimated 100 million years or more, this genetic family has been evolving alongside life to fine tune the regulation of epithelial barrier integrity ...
Maternally-derived chromosome rearrangement p: Short arm of a chromosome pat: Paternally-derived chromosome rearrangement psu dic: pseudo dicentric – only one centromere in a dicentric chromosome is active q: Long arm of a chromosome r: Ring chromosome t: Translocation: ter: Terminal end of arm (e.g. 2qter refers to the end of the long arm of ...