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Dextran is used to make microcarriers for industrial cell culture; Orally-administered dextran sodium sulphate is used to induce colitis in animal models of inflammatory bowel disease. [12] Dextran is a common model compound to test the potential of drug formulations to facilitate intestinal absorption via the paracellular route. [13]
These dextran/gelatin microspheres can be used to provide slow-release of TRAPP-Br, which is a cancer therapeutic. [8] Hydrogel microspheres synthesized by using porous chitosan polyelectrolyte complex with dextran sulfate as a cross-linker can deliver hydrophobic drugs to the intestines with high efficacy.
Dextran 70 is a type of fluid given by injection into a vein to expand blood volume. [1] Specifically it is used for shock such as that caused by bleeding or burns when blood transfusions are not quickly available. [2] However, it does not carry oxygen. [2] Common side effects include vomiting, fever, and joint pains. [2]
Dextran sulphate sodium (DSS), or dextran sodium sulphate (or any of the former with "sulfate") is a synthetic sulphated polysaccharide with anticoagulant activity used in immunological research to induce colitis. [1] [2] Dextran polymer molecules with a molecular weight of 36–50 kDa are frequently used to this end. [2]
Pharmacia, which then was still a small company, was contacted in 1943 and its CEO Elis Göth was very interested. The product Macrodex, a dextran solution, was launched four years later. [3] Dextran-based products were to play a significant role in the further expansion of Pharmacia.
Between 1972 and 2015, the average age of a new father in the U.S. rose from 27.4 to 30.9; men over 40 now account for 9% of new babies born and men over 50 nearly 1%.
While men are less likely to develop osteoporosis, it is possible and has been occurring more often in recent years in men over age 65. “Most men should aim for 1,000 - 1,200mg of calcium per ...
Over the years, various drug czars from both political parties have consulted her at Rockefeller University in New York City, where she is a professor and head of the Laboratory of the Biology of Addictive Diseases. According to Kreek, there’s no controversy over how opiate addiction acts upon the brain.