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[2] [3] Nevertheless, CVP monitoring is a useful tool to guide hemodynamic therapy. The cardiopulmonary baroreflex responds to an increase in CVP by decreasing systemic vascular resistance while increasing heart rate and ventricular contractility in dogs. [4] Trend of central venous pressure as a consequence of variations in cardiac output.
Note that, for cardiac function curve, "central venous pressure" is the independent variable and "systemic flow" is the dependent variable; for vascular function curve, the opposite is true. Venous return curves showing the normal curve when the mean systemic filling pressure (Psf) is 7 mm Hg and the effect of altering the Psf to 3.5, 7, or 14 ...
The rising central venous pressure is evidenced by distended jugular veins while in a non-supine position. It is caused by reduced diastolic filling of the right ventricle, due to pressure from the adjacent expanding pericardial sac. This results in a backup of fluid into the veins draining into the heart, most notably, the jugular veins.
The horizontal axis of Guyton diagram represents right atrial pressure or central venous pressure, and the vertical axis represents cardiac output or venous return. The red curve sloping upward to the right is the cardiac output curve, and the blue curve sloping downward to the right is the venous return curve. A steady state is formed at the ...
[1] The paradox in pulsus paradoxus is that, on physical examination , one can detect beats on cardiac auscultation during inspiration that cannot be palpated at the radial pulse . [ 1 ] It results from an accentuated decrease of the blood pressure, which leads to the (radial) pulse not being palpable and may be accompanied by an increase in ...
CVP and RAP can differ when venous tone (i.e the degree of venous constriction) is altered. This can be graphically depicted as changes in the slope of the venous return plotted against right atrial pressure (where central venous pressure increases, but right atrial pressure stays the same; VR = CVP − RAP).
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v: mean velocity of the blood; L: characteristic dimension of the vessel, in this case diameter; μ: viscosity of blood; The Reynolds number is directly proportional to the velocity and diameter of the tube. Note that NR is directly proportional to the mean velocity as well as the diameter.