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  2. List of Schedule II controlled substances (U.S.) - Wikipedia

    en.wikipedia.org/wiki/List_of_Schedule_II...

    The drug or other substance has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug or other substances may lead to severe psychological or physical dependence. The complete list of Schedule II substances is as follows.

  3. List of Schedule III controlled substances (U.S.) - Wikipedia

    en.wikipedia.org/wiki/List_of_Schedule_III...

    The drug or other substance has a potential for abuse less than the drugs or other substances in schedules I and II. The drug or other substance has a currently [1] accepted medical use in treatment in the United States. Abuse of the drug or other substance may lead to moderate or low physical dependence or high psychological dependence.

  4. List of Schedule I controlled substances (U.S.) - Wikipedia

    en.wikipedia.org/wiki/List_of_Schedule_I...

    The drug or other substance has a high potential for abuse. The drug or other substance has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug or other substance under medical supervision. The complete list of Schedule I substances is as follows. [1]

  5. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.

  6. Approved drug - Wikipedia

    en.wikipedia.org/wiki/Approved_drug

    Before a drug can be prescribed, it must undergo the FDA's approval process. While a drug can feasibly be used off-label (for non-approved indications), it still is required to be approved for a specific disease or medical condition. [2] Drug companies seeking to sell a drug in the United States must first test it.

  7. List of drugs known for off-label use - Wikipedia

    en.wikipedia.org/wiki/List_of_drugs_known_for...

    Misoprostol is approved for medical abortion regimens when administered at the office, but clinicians often give abortion patients the drug to be taken at home. [ 15 ] Modafinil is a central nervous system (CNS) stimulant medication used to treat sleepiness due to narcolepsy , shift work sleep disorder , and obstructive sleep apnea .

  8. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    In combination with palbociclib and fulvestrant for the treatment of adults with endocrine-resistant, PIK3CA-mutated, hormone receptor (HR)-positive, human epidermal growth-factor receptor 2 (HER2)-negative, locally advanced or metastatic breast cancer, as detected by an FDA-approved test, following recurrence on or after completing adjuvant ...

  9. Railroad classes - Wikipedia

    en.wikipedia.org/wiki/Railroad_classes

    In the United States, the Surface Transportation Board categorizes rail carriers into Class I, Class II, and Class III based on the carrier's annual revenue. The thresholds, last adjusted for inflation in 2019, are: [4] Class I: A carrier earning revenue greater than $504,803,294; Class II: A carrier earning revenue between $40,387,772 and ...