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Reperfusion therapy is a medical treatment to restore blood flow, either through or around, blocked arteries, typically after a heart attack (myocardial infarction (MI)). Reperfusion therapy includes drugs and surgery. The drugs are thrombolytics and fibrinolytics used in a process called thrombolysis.
A drug-eluting stent (DES) is a small mesh tube that is placed in the arteries to keep them open in the treatment of vascular disease.The stent slowly releases a drug to block cell proliferation (a biological process of cell growth and division), thus preventing the arterial narrowing that can occur after stent implantation.
The catheter/stent system is introduced into the body by penetrating a peripheral artery (an artery located in the arm or leg) and passed through the arterial system to deliver the DES into the blocked coronary artery. The stent is then expanded to dilate (open) blocked or narrowed coronary arteries (narrowed by plaque buildup), caused by a ...
The first two drug-eluting stents to be utilized were the paclitaxel-eluting stent and the sirolimus-eluting stent, both of which have received approval from the U.S. Food and Drug Administration. Most current FDA-approved drug-eluting stents use sirolimus (also known as rapamycin), everolimus and zotarolimus.
A bioresorbable stent is a tube-like device that is used to open and widen clogged heart arteries and then dissolves or is absorbed by the body. It is made from a material that can release a drug to prevent scar tissue growth. It can also restore normal vessel function and avoid long-term complications of metal stents. [1] [2]
A ureteral stent (pronounced you-REE-ter-ul), or ureteric stent, is a thin tube inserted into the ureter to prevent or treat obstruction of the urine flow from the kidney. The length of the stents used in adult patients varies between 24 and 30 cm. Additionally, stents come in differing diameters or gauges, to fit different size ureters.
[15] [16] The balloon avoids the need for a double layer of metal which is used when an in-stent restenosis is treated with another stent within the original stent. Additionally, DCB treatment does not leave an implant in the body and is designed for faster drug delivery. Alternative treatments include brachytherapy, or intracoronary radiation ...
Atherectomy is an adjunctive therapy used for lesion preparation of calcified plaque before percutaneous coronary intervention. The goal of lesion preparation with atherectomy is to modify calcified plaque, which changes the lesion compliance and allows for adequate balloon and stent expansion in segments with heavily calcified lesions. [31]