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In 1999, the FDA approved oseltamivir phosphate for the treatment of influenza in adults [68] based on two double-blind, randomized, placebo-controlled clinical trials. [69] In June 2002, the European Medicines Agency (EMA) approved oseltamivir phosphate for prophylaxis and treatment of influenza. In 2003, a pooled analysis of ten randomised ...
The selection and use of essential medicines: report of the WHO Expert Committee, 2017 (including the 20th WHO Model List of Essential Medicines and the 6th Model List of Essential Medicines for Children). Geneva: World Health Organization. hdl: 10665/259481. ISBN 978-92-4-121015-7. ISSN 0512-3054. WHO technical report series; no. 1006.
Viral neuraminidases are essential for influenza reproduction, facilitating viral budding from the host cell. Oseltamivir (Tamiflu), zanamivir (Relenza), laninamivir (Inavir), and peramivir belong to this class. Unlike the M2 inhibitors, which work only against the influenza A virus, NAIs act against both influenza A and influenza B. [1] [2] [3 ...
Treatments for influenza include a range of medications and therapies that are used in response to disease influenza.Treatments may either directly target the influenza virus itself; or instead they may just offer relief to symptoms of the disease, while the body's own immune system works to recover from infection.
The International Society for Pediatric and Adolescent Diabetes is a professional organization located in Berlin, Germany, whose aims are to promote clinical basic science, research, education and advocacy in childhood and adolescent diabetes. ISPAD publishes the journal Pediatric Diabetes. The organization was established in 1974.
Drugs used in diabetes treat types of diabetes mellitus by decreasing glucose levels in the blood. With the exception of insulin , most GLP-1 receptor agonists ( liraglutide , exenatide , and others), and pramlintide , all diabetes medications are administered orally and are thus called oral hypoglycemic agents or oral antihyperglycemic agents.
In children, influenza and respiratory syncytial virus are the two most common causes of ARDS. [17] About 3–5% of children each year develop otitis media due to influenza. [10] Adults who develop organ failure from influenza and children who have PIM scores and acute renal failure have higher rates of mortality. [17]
Live attenuated influenza vaccine (LAIV) is a type of influenza vaccine in the form of a nasal spray that is recommended for the prevention of influenza. [ 2 ] [ 7 ] It is an attenuated live vaccine, unlike other influenza vaccines, which are inactivated vaccines .