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The Allen Mouse Brain Atlas is a comprehensive genome-wide map of the adult mouse brain that reveals where each gene is expressed. [3] The mouse brain atlas was the original project of the Allen Brain Atlas and was finished in 2006. The purpose of the atlas is to aid in the development of neuroscience research.
Besides the human brain, [4] brain atlases exist for the brains of the mouse, [5] rhesus macaques, [6] Drosophila, [7] pig [8] and others. Notable examples include the Allen Brain Atlas , BrainMaps , BigBrain , Infant Brain Atlas , [ 9 ] and the work of the International Consortium for Brain Mapping (ICBM).
The house mouse (Mus musculus) has a gestation period of 19 to 21 days. Key events in mouse brain development occur both before and after birth, beginning with peak neurogenesis of the cranial motor nuclei 9 days after conception, up to eye opening which occurs after birth and about 30 days after conception.
Named the Allen Brain Atlas, it was a web-based, three-dimensional map of gene expression in the mouse brain detailing more than 21,000 genes at the cellular level. Since the project's launch, it has been renamed the Allen Mouse Brain Atlas to distinguish it from subsequent atlas projects.
Allen Brain Atlas [2] Mouse Brain Library [3] High resolution mouse brain atlas; BrainMaps. High-Resolution Brain Maps and Brain Atlases of Mus musculus; Despite superficial differences, especially in size and weight, the mouse brain and its function can serve as a powerful animal model for study of human brain diseases or mental disorders (see ...
It is hypothesized in [67] that the growing structure copies the axonal development of the human brain: the earliest developing connections (axonal fibers) are common at most of the subjects, and the subsequently developing connections have larger and larger variance, because their variances are accumulated in the process of axonal development.
For a topographic map of the visual world, the map first forms during neural development via molecular signals, such as chemospecific matching between molecular gradients. [14] The molecular basis of sensory maps and brain development is a field that is being actively explored.
The Blue Brain Project was able to model these networks using algebraic topology. [13] In 2018, Blue Brain Project released its first digital 3D brain cell atlas [14] which, according to ScienceDaily, is like "going from hand-drawn maps to Google Earth", providing information about major cell types, numbers, and positions in 737 regions of the ...