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Methylcobalamin (mecobalamin, MeCbl, or MeB 12) is a cobalamin, a form of vitamin B 12. It differs from cyanocobalamin in that the cyano group at the cobalt is replaced with a methyl group. [1] Methylcobalamin features an octahedral cobalt(III) centre and can be obtained as bright red crystals. [2]
Methylcobalamin (shown) is a form of vitamin B 12. Physically it resembles the other forms of vitamin B 12, occurring as dark red crystals that freely form cherry-colored transparent solutions in water. Vitamin B 12 is the most chemically complex of all the vitamins. [6]
Research has shown that methylcobalamin is more efficiently used and retained in the body than the cyanocobalamin form,” Gray says. ️ Read the label. The form of B12 should be clearly listed.
Enzymes that require adenosylcobalamin catalyse reactions in which the first step is the cleavage of adenosylcobalamin to form cob(II)alamin and the 5'-deoxyadenosyl radical, and thus act as radical generators. In both types of enzymes the B12-binding domain uses a histidine to bind the cobalt atom of cobalamin cofactors.
Cobalamin (vitamin B 12) is the largest and most structurally complex vitamin. It consists of a modified tetrapyrrole , a corrin, with a centrally chelated cobalt ion and is usually found in one of two biologically active forms: methylcobalamin and adenosylcobalamin .
Vitamin B12 is a power nutrient. Here's how to know if you're getting enough, how to know if you're deficient, and the best foods to eat every day for health.
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