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Lichen sclerosus (LS) is a chronic, inflammatory skin disease, of unknown cause, which can affect any body part of any person, but has a strong preference for the genitals (penis, vulva), and is also known as balanitis xerotica obliterans when it affects the penis. Lichen sclerosus is not contagious.
Vulvar intraepithelial neoplasia (VIN) refers to particular changes that can occur in the skin that covers the vulva. VIN is an intraepithelial neoplasia , and can disappear without treatment. VINs are benign but if the changes become more severe, there is a chance of cancer developing after many years, and so it is referred to as a ...
If the skin changes are not obvious on visual inspection, a biopsy of the skin may be performed to acquire an exact diagnosis. Treatment for vulvar lichen sclerosus may consist of topical hydrocortisone in mild cases, or stronger topical steroids (e.g. clobetasol propionate). Preliminary studies show that 75% of cases do not resolve with puberty.
Differentiated vulvar intraepithelial neoplasia (dVIN), which is associated with chronic skin conditions including lichen sclerosus and lichen planus and typically affects older women. This lesion progresses to keratinizing squamous cell carcinoma in approximately 33%. [22]
Kraurosis vulvae or vulvar lichen sclerosus (VLS) is a cutaneous condition characterized by atrophy and shrinkage of the skin of the vagina and vulva often accompanied by a chronic inflammatory reaction in the deeper tissues.
The ISSVD regularly promotes and develops terminology, classification, and guidelines concerning these conditions. These include, among others: vulvar dermatosis (lichen sclerosus, lichen planus), [1] [2] vulvar pain , [3] [4] [5] vulvar intraepithelial neoplasia, [6] etc. More recently, a guideline concerning female cosmetic genital surgery ...
Lichen sclerosus: Hyperkeratosis, atrophic epidermis, sclerosis of dermis and dermal lymphocytes. [7] Erythema multiforme Lupus erythematosis Typical findings in systemic lupus erythematosus: [8] Fibrinoid necrosis at the dermoepidermal junction; Liquefactive degeneration and atrophy of the epidermis; Mucin deposition in the reticular dermis
If the skin changes are not obvious on visual inspection, a biopsy of the skin may be performed to acquire an exact diagnosis. Treatment for vulvar lichen sclerosis may consist of topical hydrocortisone in mild cases, or stronger topical steroids (e.g. clobetasol propionate). Preliminary studies show that 75% of cases do not resolve with puberty.
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