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Bubonic plague 15–100 million 25–60% of European population [6] 541–549 North Africa, Europe, and Western Asia 3 Black Death: Bubonic plague: 25–50 million 30–60% of European population [7] 1346–1353 Europe, Asia, and North Africa 4 HIV/AIDS pandemic: HIV/AIDS: 43 million (as of 2024) [a] 1981–present [8] Worldwide 5 COVID-19 pandemic
Plague, one of the deadliest bacterial infections in human history, caused an estimated 50 million deaths in Europe during the Middle Ages when it was known as the Black Death.
Symptoms of the Bubonic Plague included painful and enlarged or swollen lymph nodes, headaches, chills, fatigue, vomiting, and fevers, and within 3 to 5 days, 80% of the victims would be dead. [1] Historians estimate that it reduced the total world population from 475 million to between 350 and 375 million.
The effective reproduction number or reproduction rate, symbolised with R e, is a rate of how many more people are infected from a positive COVID-19 case. In order to suppress an outbreak, the reproduction rate must be constantly below 1, which means each positive case infects less than one person. The Robert Koch Institute measures the ...
The global COVID-19 pandemicarrived in Europewith its first confirmed case in Bordeaux, France, on 24 January 2020, and subsequently spread widely across the continent. By 17 March 2020, every country in Europe had confirmed a case,[3]and all have reported at least one death, with the exception of Vatican City.
Black Death migration. Plaque in Weymouth, England. The Black Death was one of the most devastating pandemics in human history, resulting in the deaths of an estimated 75 to 200 million people in Eurasia, and peaking in Eurasia from 1321 to 1353. Its migration followed the sea and land trading routes of the medieval world.
25,000,000 – 50,000,000 (estimated) The Black Death was a bubonic plague pandemic occurring in Europe from 1346 to 1353. It was one of the most fatal pandemics in human history; as many as 50 million people [2] perished, perhaps 50% of Europe's 14th century population. [3] The disease is caused by the bacterium Yersinia pestis and spread by ...
The global COVID-19 pandemicarrived in Europewith its first confirmed case in Bordeaux, France, on 24 January 2020, and subsequently spread widely across the continent. By 17 March 2020, every country in Europe had confirmed a case,[62]and all have reported at least one death, with the exception of Vatican City.