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Schematic representation of transmembrane proteins: 1) a single-pass membrane protein 2) a multipass membrane protein (α-helix) 3) a multipass membrane protein β-sheet. The membrane is represented in light yellow. A transmembrane protein is a type of integral membrane protein that spans the entirety of the cell membrane.
The database provides information about the individual proteins including computationally generated three-dimensional models of their transmembrane alpha-helices spatially arranged in the membrane, topology, intracellular localizations, amino acid sequences, domain architecture, functional annotation and available experimental structures from ...
The largest and most common human TMEM33 protein is 247 amino acid long protein with 3 transmembrane domains. The only known TMEM33 ortholog with four transmembrane domains is Tts1 in Schizosaccharomyces pombe. The human protein has a predicted molecular weight of 28 kDa and an isoelectric point of 9.88.
329909 Ensembl ENSG00000143001 ENSMUSG00000085933 UniProt Q8N0U2 n/a RefSeq (mRNA) NM_182532 NM_001370848 RefSeq (protein) NP_872338 n/a Location (UCSC) Chr 1: 54.98 – 54.99 Mb Chr 4: 106.36 – 106.4 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transmembrane protein 61 (TMEM61) is a protein that is encoded by the TMEM61 gene in humans. It is located on the first chromosome in ...
112441426 115490131 Ensembl ENSG00000273238 n/a UniProt n a n/a RefSeq (mRNA) NM_001362796 XM_030254964 RefSeq (protein) n/a n/a Location (UCSC) Chr 4: 0.57 – 0.58 Mb n/a PubMed search Wikidata View/Edit Human View/Edit Mouse Figure 1: Map of Chromosome 4 Transmembrane protein 271, or TMEM271 is a protein in Homo sapiens encoded by the TMEM271 gene, located at 4p16.3 on the minus strand. The ...
The Transporter Classification Database (or TCDB) is an International Union of Biochemistry and Molecular Biology (IUBMB)-approved classification system for membrane transport proteins, including ion channels.
Prediction of transmembrane helices to identify transmembrane proteins. [111] 2001 TMPred: The TMpred program makes a prediction of membrane-spanning regions and their orientation. The algorithm is based on the statistical analysis of TMbase, a database of naturally occurring transmembrane proteins (bio.tools entry) [112]
TMEM128, also known as Transmembrane Protein 128, is a protein that in humans is encoded by the TMEM128 gene. TMEM128 has three variants, varying in 5' UTR 's and start codon location. [ 5 ] TMEM128 contains four transmembrane domains and is localized in the Endoplasmic Reticulum membrane.