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2. SGLT2 inhibitor - Wikipedia

   en.wikipedia.org/wiki/SGLT2_inhibitor

   Sotagliflozin (Inpefa) is a dual SGLT1/SGLT2 inhibitor approved by the US Food and Drug Administration (FDA) in May 2023, to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, chronic kidney disease, and other cardiovascular risk factors ...

3. Dapagliflozin - Wikipedia

   en.wikipedia.org/wiki/Dapagliflozin

   Dapagliflozin is used along with diet, exercise, and usually with other glucose-lowering medications, to improve glycaemic control in adults with type 2 diabetes. . Dapagliflozin, in addition to other SGLT2-inhibitors, was shown to reduce the rate of decline in kidney function and kidney failure in non-diabetic and type 2 diabetic adults when added to the existing treatment

4. GLP-1 receptor agonist - Wikipedia

   en.wikipedia.org/wiki/GLP-1_receptor_agonist

   GLP-1 agonists were developed initially for type 2 diabetes. [5] The 2022 American Diabetes Association (ADA) standards of medical care in diabetes include GLP-1 agonist or SGLT2 inhibitor as a first line pharmacological therapy for type 2 diabetes in patients who have or are at high risk for atherosclerotic cardiovascular disease or heart failure.

5. New Phase III Data Showed Dapagliflozin Significantly ... - AOL

   www.aol.com/2013/09/24/new-phase-iii-data-showed...

   New Phase III Data Showed Dapagliflozin Significantly Reduced HbA1c Compared to Placebo at 24 Weeks in Patients with Type 2 Diabetes Inadequately Controlled with the Combination of Metformin Plus ...

6. Cardiotonic agent - Wikipedia

   en.wikipedia.org/wiki/Cardiotonic_agent

   [77] [78] Heart failure can manifest in its life-threatening form of cardiogenic shock, with hypotension and low blood flow (hypoperfusion), placing the patient at risk of multiorgan failure. [79] In cardiogenic shock management, cardiotonic agents serve 2 functions.

7. Deepak L. Bhatt - Wikipedia

   en.wikipedia.org/wiki/Deepak_L._Bhatt

   Name, sponsor, role Description SOLOIST, Sanofi Lexicon, Chair [15] Randomized controlled clinical trial (RCT) of sotagliflozin versus placebo in patients with diabetes and acute decompensated heart failure. SCORED, Sanofi Lexicon, Chair [16] RCT of sotagliflozin versus placebo in patients with diabetes and at high cardiovascular risk.

8. Heart failure is reversed with new gene therapy in animal ...

   www.aol.com/heart-failure-reversed-gene-therapy...

   Heart failure has historically been irreversible, but a new study suggests that could change. At the University of Utah, scientists used a new gene therapy that reversed heart failure in animals ...

9. Dapagliflozin/metformin - Wikipedia

   en.wikipedia.org/wiki/Dapagliflozin/metformin

   Canagliflozin, dapagliflozin, and empagliflozin should each be stopped at least three days before, and ertugliflozin should be stopped at least four days before scheduled surgery. [ 8 ] Symptoms of ketoacidosis include nausea, vomiting, abdominal pain, tiredness, and trouble breathing.