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N-terminal prohormone of brain natriuretic peptide (NT-proBNP or BNPT) is a 76 amino acid long protein that is cleaved from the N-terminal end of the 108 amino acid long prohormone proBNP to release brain natriuretic peptide 32 (BNP, also known as B-type natriuretic peptide). [1] [2] [3] [4]
Proprotein convertase 1, also known as prohormone convertase, prohormone convertase 3, or neuroendocrine convertase 1 and often abbreviated as PC1/3 is an enzyme that in humans is encoded by the PCSK1 gene. [5] PCSK1 and PCSK2 differentially cleave proopiomelanocortin and they act together to process proinsulin and proglucagon in pancreatic ...
In the context of racing, nitrous oxide is often termed nitrous or NOS.The term NOS is derived from the initials of the company name Nitrous Oxide Systems, Inc. (now a brand of Holley Performance Products) one of the pioneering companies in the development of nitrous oxide injection systems for automotive performance use, and has become a genericized trademark.
The right side shows protein hormones (1) binding with receptors which (2) begins a transduction pathway. The transduction pathway ends (3) with transcription factors being activated in the nucleus, and protein synthesis beginning. In both diagrams, a is the hormone, b is the cell membrane, c is the cytoplasm, and d is the nucleus.
A prohormone is a committed precursor of a hormone consisting of peptide hormones synthesized together that has a minimal hormonal effect by itself because of its expression-suppressing structure, often created by protein folding and binding additional peptide chains to certain ends, that makes hormone receptor binding sites located on its peptide hormone chain segments inaccessible.
A preprohormone is the precursor protein to one or more prohormones, which are in turn precursors to peptide hormones. [1] In general, the protein consists of the amino acid chain that is created by the hormone-secreting cell, before any changes have been made to it.
Specific endopeptidases in the cell cleave the prohormone just before it is released into the bloodstream, generating the mature hormone form of the molecule. Mature peptide hormones then travel through the blood to all of the cells of the body, where they interact with specific receptors on the surfaces of their target cells.
[c] These are supplementary pumps and do not replace the main, mechanical, oil pump. Electric pump as a main engine pump again will require big electric motors and it may be simply cheaper to drive directly from the engine. For e.g. BMW S65 engine's oil pump delivers ca. 45 LPM (Litres Per Minute) of oil at 5.5 bar pressure. [5]