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All PDE5 inhibitors are generally well tolerated. [1] The occurrence of side effects, or adverse drug reactions (ADRs), with PDE5 inhibitors depends on the dose and type of agent. [1] Headache is a very common ADR, occurring in >10% of patients. Other common ADRs include: dizziness, flushing, dyspepsia, nasal congestion or rhinitis. [6]
PDE5 inhibitors are not routinely prescribed as first line treatment for erectile dysfunction. This is as they cause unwanted side effects like hair loss, headache, and nausea (among others). Often, erectile dysfunction can instead be treated non-pharmacologically, by identifying and addressing a psychogenic cause of the disease. [18]
[1] [4] PDE5 inhibitors increase NO and are approved for erectile dysfunction, pulmonary arterial hypertension (PAH), and benign prostatic hyperplasia, but they are less effective in patients for whom NO production is suppressed, such as people with diabetes or obesity.
Viagra (Sildenafil): Uses, Benefits and Side Effects. This article was reviewed by Kelly Brown MD, MBA. ... but today, the primary use of this PDE5 inhibitor is to remedy ED. Other first-line ...
As mentioned, Cialis can interact with other PDE5 inhibitors for ED, as well as medications prescribed to treat hypertension (high blood pressure), fungal infections, heart disease, heart failure ...
The term erectile dysfunction does not encompass other erection-related disorders, such as priapism. Treatment of ED encompasses addressing the underlying causes, lifestyle modification, and addressing psychosocial issues. [4] In many instances, medication-based therapies are used, specifically PDE5 inhibitors like sildenafil. [13]
Avanafil is a PDE5 inhibitor that’s less likely to cause side effects than older medications and begins working faster. ... If you’re looking for the best medicine for erectile dysfunction ...
Avanafil is a PDE5 inhibitor approved for erectile dysfunction by the FDA on April 27, 2012 [2] and by EMA on June 21, 2013. [3] Avanafil is sold under the brand names Stendra and Spedra.
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