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There was no clear view on the relationship between carbolic acid and creosote; Runge described it as having similar caustic and antiseptic properties, but noted that it was different, in that it was an acid and formed salts. Nonetheless, Reichenbach argued that creosote was also the active element, as it was in pyroligneous acid.
In 1834, German chemist Friedlieb Ferdinand Runge discovered a phenol, also known as carbolic acid, which he derived in an impure form from coal tar.In August 1865, Joseph Lister applied a piece of lint dipped in carbolic acid solution to the wound of an eleven-year-old boy at Glasgow Royal Infirmary, who had sustained a compound fracture after a cart wheel had passed over his leg.
Phenol (also known as carbolic acid, phenolic acid, or benzenol) is an aromatic organic compound with the molecular formula C 6 H 5 OH. [5] It is a white crystalline solid that is volatile . The molecule consists of a phenyl group ( −C 6 H 5 ) bonded to a hydroxy group ( −OH ).
The residue remaining in the autoclave vessel is a dark, syrupy mass called creosote, which is composed mainly of phenolic acid and cresylic acid. The original composition of creolin is a creosote tar oil, caustic soda, soaps, and very little water. It is of low technology and a very powerful disinfectant. [1]
Unilever in Cyprus and Trinidad and Tobago manufactures Red Lifebuoy Soap with a carbolic fragrance, but as of 1976, it no longer contains phenol. [citation needed] The Lifebuoy soap manufactured in India and Indonesia for other markets, including South and South East Asia, has been updated to use red and other colours with 'modern' aromas. [4]
Carbolic soap, 19th-century. The original Lysol formulation, essentially a water solution of carbolic soap. [11] "Lysol" has been used as a generic trademark to refer to such a cresol soap solution and remains used as such in some professional settings. The CAS number is 12772-68-8.
Coal tar creosote; Wood creosote; Reduction product of vanillin using zinc powder in strong hydrochloric acid (Clemmensen reduction) Found as glycosides in green vanilla beans [2] It is also found in tequila. [3]
The antiseptic properties of phenol discovered by Jules Lemaire were put to good use by the British surgeon Joseph Lister (1827–1912), pioneer of the antiseptic method in operative surgery, who had the idea of putting all his surgical tools and gowns in carbolic acid, as well as the wounds of the operated, thus reducing the postoperative mortality rate from 40% to 15%.