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Fundic gland polyposis is a medical syndrome where the fundus and the body of the stomach develop many fundic gland polyps. The condition has been described both in patients with familial adenomatous polyposis (FAP) and attenuated variants (AFAP), and in patients in whom it occurs sporadically.
A fundic gland polyp is a type of polyp, found in the fundus of the stomach. Fundic gland polyps are found in 0.8 to 1.9% of patients who undergo esophagogastroduodenoscopy, and are more common in middle-aged women. [2] The risk of malignancy is very low or none, when sporadic. [3] Fundic gland polyposis is a medical syndrome with multiple ...
Familial adenomatous polyposis (FAP) is an autosomal dominant inherited condition in which numerous adenomatous polyps form mainly in the epithelium of the large intestine. While these polyps start out benign, malignant transformation into colon cancer occurs when they are left untreated.
Fundic gland polyposis is a medical syndrome where the fundus and the body of the stomach develop many fundic gland polyps. Pernicious anemia is caused when damaged parietal cells fail to produce the intrinsic factor necessary for the absorption of vitamin B12. This is the most common cause of vitamin B12 deficiency.
Gardner's syndrome (also known as Gardner syndrome, familial polyposis of the colon, [1] or familial colorectal polyposis [2]) is a subtype of familial adenomatous polyposis (FAP). Gardner syndrome is an autosomal dominant form of polyposis characterized by the presence of multiple polyps in the colon together with tumors outside the colon. [ 3 ]
A horizontal line across from the cardiac notch gives the dome-shaped region called the fundus. [8] The cardia is a very small region of the stomach that surrounds the esophageal opening. [8] The fundus (from Latin 'bottom') is formed in the upper curved part. The body or corpus is the main, central region of the stomach.
FAP spawns from a mutation located on chromosome 5q21.1, this mutation is the adenomatous polyposis coli (APC)— a tumor suppressor gene. [11] It is a condition in which hundreds of polyps are found within the colon through a colonoscopy that, if left untreated, can lead to colorectal cancer. [5]
Cronkhite–Canada syndrome is a rare syndrome characterized by multiple polyps of the digestive tract. It is sporadic (i.e. it does not seem to be a hereditary disease), [1] and it is currently considered acquired [2] and idiopathic (i.e. cause remains unknown). About two-thirds of patients are of Japanese descent and the male to female ratio ...