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Hydroxyapatite is widely used within dentistry and oral and maxillofacial surgery, due to its chemical similarity to hard tissue. [34] In the future, there are possibilities for using nano-hydroxyapatite for tissue engineering and repair. The main and most advantageous feature of nano-hydroxyapatite is its biocompatibility. [35]
Tooth enamel consists mostly of calcium hydroxyphosphate, Ca 5 (PO 4) 3 OH, also known as the mineral hydroxyapatite. Apatite is a hard, insoluble compound. Apatite is a hard, insoluble compound. Acid (H + ), produced especially after a high-sugar meal, attacks the apatite:
P11-4 is a self-assembling β-peptide. It builds a 3-D bio-matrix with binding sites for Calcium-ions serving as nucleation point for hydroxyapatite (tooth mineral) formation. The high affinity to tooth mineral is based on matching distances of Ca-ion binding sites on P11-4 and Ca spacing in the crystal lattice of hydroxyapatite.
Toothpaste has important benefits for oral health, but just the mechanical action of brushing with a toothbrush alone will remove the buildup of plaque, the sticky biofilm of bacteria on teeth ...
Topical fluorides are fluoride-containing drugs indicated in prevention and treatment of dental caries, particularly in children's primary dentitions. [1] The dental-protecting property of topical fluoride can be attributed to multiple mechanisms of action, including the promotion of remineralization of decalcified enamel, the inhibition of the cariogenic microbial metabolism in dental plaque ...
In 1980, the Japanese company, Sangi Co., Ltd., launched APADENT, the world's first remineralizing toothpaste to use a nano-form of hydroxyapatite, the main component of tooth enamel, rather than fluoride, to remineralize areas of mineral loss below the surface of tooth enamel (incipient caries lesions).
Various commercially available mouth rinses have been tested for their inhibitory effects on biofilm formation over a 24-hour period. [3] By slowing the formation of biofilms, individuals who use Biotène may reduce the risk of dental caries and other oral diseases that can arise from xerostomia and bacterial accumulation, thus improving both ...
As of 2006, no controlled study of the effects of chewing gum containing potassium chloride has been made, although it has been reported as significantly reducing dentine hypersensitivity. Nano-hydroxyapatite (nano-HAp) is considered one of the most biocompatible and bioactive materials and has gained wide acceptance in dentistry in recent years.
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