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Cushing's disease most commonly refers to pituitary-dependent hyperadrenocorticism, the most common condition of Cushing's syndrome, but 'Cushing's' is used to refer to all hyperadrenocorticism conditions. [2] Cats are less likely to be diagnosed than dogs. [2] Cushing's occurs infrequently in hamsters. It may be more common but due to hamsters ...
In 40-50% of dogs with Cushing's syndrome thyroxine and triiodothyronine levels are decreased. Cushing's is a potential differential diagnosis for hypothyroidism when the patient presents with endocrine alopecia. Clinical history can be used to differentiate the two: polyuria, polydipsia, and polyphagia are symptoms of Cushing's but not ...
PNP deficiency is inherited in an autosomal recessive manner. [1] This means the defective gene responsible for the disorder is located on an autosome (chromosome 14 is an autosome), and two copies of the defective gene (one inherited from each parent) are required in order to be born with the disorder.
Type 1 von Willebrand Disease in dogs. Type 1 von Willebrand Disease is the most common type, and also the mildest. It occurs when dogs have a mild deficiency in all the proteins making up their ...
Cushing's syndrome is a collection of signs and symptoms due to prolonged exposure to glucocorticoids such as cortisol. [4] [9] [10] Signs and symptoms may include high blood pressure, abdominal obesity but with thin arms and legs, reddish stretch marks, a round red face due to facial plethora, [11] a fat lump between the shoulders, weak muscles, weak bones, acne, and fragile skin that heals ...
Sudden acquired retinal degeneration (SARD) is a disease in dogs causing sudden blindness. It can occur in any breed. The cause is unknown, but possibly involves either autoimmune disease, a toxin, or Cushing's disease. [69] Symptoms include sudden permanent blindness, dilated pupils, and loss of the pupillary light reflex. [63]
Nelson's syndrome is a disorder that occurs in about one in four patients who have had both adrenal glands removed to treat Cushing's disease. [1] In patients with pre-existing adrenocorticotropic hormone ()-secreting pituitary adenomas, loss of adrenal feedback following bilateral adrenalectomy can trigger the rapid growth of the tumor, leading to visual symptoms (e.g. bitemporal hemianopsia ...
It may also occur in the setting of hyperparathyroidism, hypothyroidism, and Cushing syndrome. [1] It is diagnosed based on a blood phosphate concentration of less than 0.81 mmol/L (2.5 mg/dL). [1] When levels are below 0.32 mmol/L (1.0 mg/dL) it is deemed to be severe. [2] Treatment depends on the underlying cause. [1]
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