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Systems biology is the computational and mathematical analysis and modeling of complex biological systems.It is a biology-based interdisciplinary field of study that focuses on complex interactions within biological systems, using a holistic approach (holism instead of the more traditional reductionism) to biological research.
Systems biology, in this sense, is still in its infancy [citation needed]. There is great interest in network medicine for the modelling biological systems. This article focuses on inference of biological network structure using the growing sets of high-throughput expression data for genes, proteins, and metabolites. [10]
Mathematical and theoretical biology, or biomathematics, is a branch of biology which employs theoretical analysis, mathematical models and abstractions of living organisms to investigate the principles that govern the structure, development and behavior of the systems, as opposed to experimental biology which deals with the conduction of ...
In the context of a biological system, bifurcation theory describes how small changes in an input parameter can cause a bifurcation or qualitative change in the behavior of the system. The ability to make dramatic change in system output is often essential to organism function, and bifurcations are therefore ubiquitous in biological networks ...
Examples of degeneracy are found in the genetic code, when many different nucleotide sequences encode the same polypeptide; in protein folding, when different polypeptides fold to be structurally and functionally equivalent; in protein functions, when overlapping binding functions and similar catalytic specificities are observed; in metabolism, when multiple, parallel biosynthetic and ...
A biological network is a method of representing systems as complex sets of binary interactions or relations between various biological entities. [1] In general, networks or graphs are used to capture relationships between entities or objects. [1]
In their 1972 book Autopoiesis and Cognition, Chilean biologists Maturana and Varela described how they invented the word autopoiesis. [4]: 89 : 16 "It was in these circumstances ... in which he analyzed Don Quixote's dilemma of whether to follow the path of arms (praxis, action) or the path of letters (poiesis, creation, production), I understood for the first time the power of the word ...
Also called functionalism. The Darwinian view that many or most physiological and behavioral traits of organisms are adaptations that have evolved for specific functions or for specific reasons (as opposed to being byproducts of the evolution of other traits, consequences of biological constraints, or the result of random variation). adaptive radiation The simultaneous or near-simultaneous ...