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  2. Dehydroepiandrosterone - Wikipedia

    en.wikipedia.org/wiki/Dehydroepiandrosterone

    Women with complete androgen insensitivity syndrome (CAIS), who have a non-functional androgen receptor (AR) and are immune to the androgenic effects of DHEA and other androgens, have absent or only sparse/scanty pubic and axillary hair and body hair in general, demonstrating the role of DHEA and other androgens in body hair development at both ...

  3. Hyperandrogenism - Wikipedia

    en.wikipedia.org/wiki/Hyperandrogenism

    Hyperandrogenism is a medical condition characterized by high levels of androgens.It is more common in women than men. [4] Symptoms of hyperandrogenism may include acne, seborrhea, hair loss on the scalp, increased body or facial hair, and infrequent or absent menstruation.

  4. Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

    en.wikipedia.org/wiki/Congenital_adrenal...

    Can cause androgen effects and infertility in adolescent and adult women. Cortisol is mildly reduced depending on genotype, [104] but aldosterone is not. Patients who are genetically found to have nonclassical CAH but are asymptomatic No symptoms of androgen excess, levels of androgens are within the normal range.

  5. Hirsutism - Wikipedia

    en.wikipedia.org/wiki/Hirsutism

    Cushing syndrome occurs when there is an endogenous or exogenous elevated levels of cortisol. One cause of endogenous Cushing syndrome is an adrenocorticotrophic hormone-secreting pituitary adenoma that is responsible for high secretion of not just cortisol but also androgens from the pituitary gland. [24]

  6. Steroid hormone - Wikipedia

    en.wikipedia.org/wiki/Steroid_hormone

    The natural steroid hormones are generally synthesized from cholesterol in the gonads and adrenal glands. These forms of hormones are lipids . They can pass through the cell membrane as they are fat-soluble, [ 7 ] and then bind to steroid hormone receptors (which may be nuclear or cytosolic depending on the steroid hormone) to bring about ...

  7. Adrenocortical hormone - Wikipedia

    en.wikipedia.org/wiki/Adrenocortical_hormone

    In addition to hypersecretion of cortisol, excess androgens are secreted. [8] In females, increased secretion of androgens, such as testosterone, results in masculinization which may present as facial hair growth and a deepened voice. [2] Treatment for Cushing's syndrome aims to reduce the high levels of cortisol circulating through the human body.

  8. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of_spiro...

    A 1991 review reported that the influences of spironolactone on androgen levels in women were variable and inconsistent. [78] Spironolactone has shown no significant effect on levels of testosterone, estradiol, luteinizing hormone, and follicle-stimulating hormone in men. [146] [78]

  9. Cortisone reductase deficiency - Wikipedia

    en.wikipedia.org/wiki/Cortisone_reductase_deficiency

    In a healthy body, blood cortisone and cortisol levels are roughly equimolar. [7] Cortisone reductase deficiency leads to an elevated level of inert cortisone to active cortisol in adipose tissue. Cortisone reductase deficiency is caused by dysregulation of the 11β-hydroxysteroid dehydrogenase type 1 enzyme, otherwise known as cortisone reductase.

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