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Before implementing continuous renal replacement therapy (CRRT), acute renal failure (ARF) in critically ill, multiple organ failure patients was managed by intermittent hemodialysis and the mortality rate was very high. [4] Hemodialysis is effective in clearance and ultrafiltration, but it has deleterious effects on hemodynamic stability. [5]
Hemofiltration is sometimes used in combination with hemodialysis, when it is termed hemodiafiltration. Blood is pumped through the blood compartment of a high flux dialyzer, and a high rate of ultrafiltration is used, so there is a high rate of movement of water and solutes from blood to dialysate that must be replaced by substitution fluid that is infused directly into the blood line.
Dialysis disequilibrium syndrome (DDS) is the collection of neurological signs and symptoms, attributed to cerebral edema, during or following shortly after intermittent hemodialysis [1] or CRRT.
Indications for dialysis in a patient with acute kidney injury are summarized with the vowel mnemonic of "AEIOU": [17] Acidemia from metabolic acidosis in situations in which correction with sodium bicarbonate is impractical or may result in fluid overload. Electrolyte abnormality, such as severe hyperkalemia, especially when combined with AKI.
Indications can impact the pricing of medications through Value-based Pricing, also known as indication specific pricing or indication value-based pricing. [ 15 ] [ 16 ] Since drugs can be used for different indications, this form of pricing would set different prices for each indication based on the value the drug offers for whatever it is ...
Hemodialysis, also spelled haemodialysis, or simply dialysis, is a process of filtering the blood of a person whose kidneys are not working normally. This type of dialysis achieves the extracorporeal removal of waste products such as creatinine and urea and free water from the blood when the kidneys are in a state of kidney failure.
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The abbreviation CRRT may refer to: Christopher Reuel Tolkien; Carrier Route mail sorting system for the United States Postal Service; Continuous renal replacement therapy; Chemical-Biological-Radiological Rapid Response Team; Commuter Rail Real Time data from the MBTA, providing train locations and arrival predictions for the MBTA Commuter ...