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Atipamezole, sold under the brand name Antisedan among others, is a synthetic α 2 adrenergic receptor antagonist used for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. Its reversal effect works by competing with the sedative for α 2-adrenergic receptors and displacing them.
Ketamine potentiates the sedative effects of propofol [85] and midazolam. [86] Naltrexone potentiates psychotomimetic effects of a low dose of ketamine, [87] while lamotrigine [38] and nimodipine [39] decrease them. Clonidine reduces the increase of salivation, heart rate, and blood pressure during ketamine anesthesia and decreases the ...
Ketamine has been demonstrated to produce lasting antidepressant effects after administration in a clinical setting. In 2019, esketamine, an NMDA antagonist enantiomer of ketamine, was approved for use as an antidepressant in the United States. [17] In 2022, Auvelity was approved by the FDA for the treatment of depression.
Last fall, the FDA put out a warning on some types of ketamine, saying the drug is not approved for any psychiatric disorder and warned about taking it at home, which can be even more risky ...
Ketamine is a drug that was approved in 1970 by the Food and Drug Administration (FDA) for use as an anesthetic. ... One of the side effects of taking ketamine recreationally is falling into what ...
The finding by the Los Angeles County medical examiner that "Friends" star Matthew Perry died from "acute effects" of ketamine is generating interest in the drug. Ketamine is generally safe when ...
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