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  2. Atipamezole - Wikipedia

    en.wikipedia.org/wiki/Atipamezole

    Atipamezole, sold under the brand name Antisedan among others, is a synthetic α 2 adrenergic receptor antagonist used for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. Its reversal effect works by competing with the sedative for α 2-adrenergic receptors and displacing them.

  3. Ketamine - Wikipedia

    en.wikipedia.org/wiki/Ketamine

    Ketamine potentiates the sedative effects of propofol [85] and midazolam. [86] Naltrexone potentiates psychotomimetic effects of a low dose of ketamine, [87] while lamotrigine [38] and nimodipine [39] decrease them. Clonidine reduces the increase of salivation, heart rate, and blood pressure during ketamine anesthesia and decreases the ...

  4. NMDA receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/NMDA_receptor_antagonist

    Ketamine has been demonstrated to produce lasting antidepressant effects after administration in a clinical setting. In 2019, esketamine, an NMDA antagonist enantiomer of ketamine, was approved for use as an antidepressant in the United States. [17] In 2022, Auvelity was approved by the FDA for the treatment of depression.

  5. What is ketamine? Understanding the drug after Matthew ... - AOL

    www.aol.com/ketamine-understanding-drug-matthew...

    Last fall, the FDA put out a warning on some types of ketamine, saying the drug is not approved for any psychiatric disorder and warned about taking it at home, which can be even more risky ...

  6. How ketamine therapy is different from recreational use - AOL

    www.aol.com/lifestyle/matthew-perry-underwent...

    Ketamine is a drug that was approved in 1970 by the Food and Drug Administration (FDA) for use as an anesthetic. ... One of the side effects of taking ketamine recreationally is falling into what ...

  7. What is ketamine? Understanding the drug cited in Matthew ...

    www.aol.com/news/ketamine-understanding-drug...

    The finding by the Los Angeles County medical examiner that "Friends" star Matthew Perry died from "acute effects" of ketamine is generating interest in the drug. Ketamine is generally safe when ...

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