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Clonidine, sold under the brand name Catapres among others, is an α 2A-adrenergic receptor agonist [12] medication used to treat high blood pressure, ADHD, drug withdrawal (e.g., alcohol, opioids, or nicotine), menopausal flushing, diarrhea, spasticity, and certain pain conditions. [13]
Clonidine has shown promise among patients with anxiety, panic and PTSD in clinical trials and was used to treat severely and chronically abused and neglected preschool children. It improved disturbed behavior by reducing aggression, impulsivity, emotional outbursts, and oppositionality. [ 6 ]
The anxiety symptoms are usually persistent and constant. Patients of this disorder could experience excessive anxiety for a long duration, commonly over six months and the symptoms could occur without any specific triggers. Panic disorder: This disorder specifically refers to the suffering from panic attacks and also the fear of repetitive ...
This is a list of investigational anxiolytics, or anxiolytics that are currently under development for clinical use but are not yet approved.Chemical/generic names are listed first, with developmental code names, synonyms, and brand names in parentheses.
Guanfacine is also used off-label to treat tic disorders, anxiety disorders such as generalized anxiety disorder, and PTSD. [14] Guanfacine and other α 2A -adrenergic receptor agonists have anxiolytic -like action, [ 24 ] thereby reducing the emotional responses of the amygdala , and strengthening prefrontal cortical regulation of emotion ...
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