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Schizophrenia is a debilitating and often misunderstood disorder that affects up to 1% of the world's population. [1] Although schizophrenia is a heavily studied disorder, it has remained largely impervious to scientific understanding; epigenetics offers a new avenue for research, understanding, and treatment.
Schizophrenia is a mental disorder [17] [7] characterized variously by hallucinations (typically, hearing voices), delusions, disorganized thinking and behavior, [10] and flat or inappropriate affect. [7] Symptoms develop gradually and typically begin during young adulthood and are never resolved.
Cognitive symptoms of schizophrenia involve disturbances in executive functions, working memory impairment, and inability to sustain attention. [1] Given the high numbers of individuals diagnosed with schizophrenia (nearly 1% of modern-day populations), it is unlikely that the disorder has arisen solely from random mutations. [2]
Schizophrenia presents significant challenges, but with diagnosis, treatment, and support, individuals can manage symptoms and lead fulfilling lives.
People with schizophrenia can have a job or actually speak to people or can do things themselves," said Hammer. Schizophrenia is a brain disease and patients' symptoms run a spectrum.
A Times reporter and photographer spent months chronicling the life of a man living with schizophrenia. Schizophrenia is a black box. How — and why — we reported Anthony's story
More than 40 percent of all people with schizophrenia end up in supervised group housing, nursing homes or hospitals. Another 6 percent end up in jail, usually for misdemeanors or petty crimes, while an equal proportion end up on the streets. Among researchers, schizophrenia has long been known as the “graveyard of psychiatric research.”
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
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