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The most common side effects of bicalutamide monotherapy in men are breast pain/tenderness and gynecomastia. [11] These side effects may occur in as many as 90% of men treated with bicalutamide monotherapy, [29] but gynecomastia is generally reported to occur in 70 to 80% of patients. [30]
[102] [105] [22] [106] Other side effects that have been observed in men and that are similarly related to androgen deprivation include hot flashes, sexual dysfunction (e.g., loss of libido, erectile dysfunction), depression, fatigue, weakness, and anemia. [102] [107] [108] However, most men have preserved sexual function with bicalutamide ...
Dapoxetine. Dapoxetine, marketed as Priligy, among others, is a selective serotonin reuptake inhibitor (SSRI) used for the treatment of premature ejaculation (PE) in men 18–64 years old. [3][4][5] Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin's action at the postsynaptic cleft, and as a consequence promoting ...
Erectile dysfunction (ED), also referred to as impotence, is a form of sexual dysfunction in males characterized by the persistent or recurring inability to achieve or maintain a penile erection with sufficient rigidity and duration for satisfactory sexual activity.
Men who reported severe erectile dysfunction—difficulty getting and keeping an erection—improved 4.9 points on a scale of 6-30, with higher scores indicating better function.
[1] [36] In the US, biotin as a non-prescription dietary supplement is sold in amounts of 1 to 10 mg per serving, with claims for supporting hair and nail health, and as 300 mg per day as a possibly effective treatment for multiple sclerosis [37] [38] (see § Research). Overconsumption of 5 mg/day or higher causes elevated concentration in ...
Post-SSRI sexual dysfunction (PSSD) [62] [63] refers to a set of symptoms reported by some people who have taken SSRIs or other serotonin reuptake-inhibiting (SRI) drugs, in which sexual dysfunction symptoms persist for at least three months [64] [65] [66] after ceasing to take the drug. The status of PSSD as a legitimate and distinct pathology ...
In any case, common side effects of antiandrogens in men include breast tenderness, breast enlargement, feminization, hot flashes, sexual dysfunction, infertility, and osteoporosis. In women, antiandrogens are much better tolerated , and antiandrogens that work only by directly blocking androgens are associated with minimal side effects.
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