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In neuroscience, the reward system is a collection of brain structures and neural pathways that are responsible for reward-related cognition, including associative learning (primarily classical conditioning and operant reinforcement), incentive salience (i.e., motivation and "wanting", desire, or craving for a reward), and positively-valenced emotions, particularly emotions that involve ...
The nucleus accumbens is located in the ventral striatum and integrates information from cortical and limbic brain structures to mediate behaviors the reinforce reward. [16] It is a major target for the dopaminergic projections from the VTA, a group of neurons located close to the midline on the floor of the midbrain .
Dopaminergic pathways (dopamine pathways, dopaminergic projections) in the human brain are involved in both physiological and behavioral processes including movement, cognition, executive functions, reward, motivation, and neuroendocrine control. [1] Each pathway is a set of projection neurons, consisting of individual dopaminergic neurons.
The nucleus accumbens (NAc or NAcc; also known as the accumbens nucleus, or formerly as the nucleus accumbens septi, Latin for ' nucleus adjacent to the septum ') is a region in the basal forebrain rostral to the preoptic area of the hypothalamus. [1] The nucleus accumbens and the olfactory tubercle collectively form the ventral striatum.
The limbic system, also known as the paleomammalian cortex, is a set of brain structures located on both sides of the thalamus, immediately beneath the medial temporal lobe of the cerebrum primarily in the forebrain. [1] Its various components support a variety of functions including emotion, behavior, long-term memory, and olfaction.
Damage to the mammillothalamic tract, ventral anterior nucleus, and ventral lateral nucleus can result in memory and language impairment. [11] Amnesia can be a result of disconnection of the mammillary bodies from the Papez circuit. [12] The fornix is a bundle of nerve tracts made of white matter. It is crucial in normal cognitive functions.
Particularly, one division within the ventral striatum, the nucleus accumbens core, is involved in the consolidation, retrieval and reconsolidation of drug memory. [9] The caudate nucleus is thought to assist in learning and memory of associations taught during operant conditioning. Specifically, research has shown that this part of the basal ...
These neural fibres connect the septal area in forebrain with medial hypothalamus. The medial forebrain bundle (MFB) is a neural pathway containing fibers from the basal olfactory regions, the periamygdaloid region and the septal nuclei, as well as fibers from brainstem regions, including the ventral tegmental area and nigrostriatal pathway.