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Copper aspirinate can be prepared by several methods. In one route of preparation, an excess of acetylsalicylic acid is dissolved in aqueous sodium carbonate. Sodium hydroxide is not suitable for this purpose, because it will hydrolyse acetylsalicylic acid (ASA) into salicylic acid and sodium acetate.
Salicylic acid has long been a key starting material for making acetylsalicylic acid (ASA or aspirin). [8] ASA is prepared by the acetylation of salicylic acid with the acetyl group from acetic anhydride or acetyl chloride. [17] ASA is the standard to which all the other non-steroidal anti-inflammatory drugs are compared. In veterinary medicine ...
Aspirin is also used long-term to help prevent further heart attacks, ischaemic strokes, and blood clots in people at high risk. [11] For pain or fever, effects typically begin within 30 minutes. [11] Aspirin works similarly to other NSAIDs but also suppresses the normal functioning of platelets. [11] One common adverse effect is an upset ...
Recrystallization: In analytical and synthetic chemistry work, purchased reagents of doubtful purity may be recrystallised, e.g. dissolved in a very pure solvent, and then crystallized, and the crystals recovered, in order to improve and/or verify their purity.
The Kolbe–Schmitt reaction proceeds via the nucleophilic addition of a phenoxide, classically sodium phenoxide (NaOC 6 H 5), to carbon dioxide to give the salicylate. The final step is the reaction (protonation) of the salicylate anion with an acid to form the desired salicylic acids (ortho- and para- isomers).
Aspirin "weakens the stomach's protective lining against stomach acid, making the stomach and intestines more vulnerable to ulcers, which can bleed," according to Harvard Health.
This WikiProject aims to provide high-quality, standardized articles in Wikipedia for all important chemicals, similar to the Merck Index.This comprises all organic and inorganic compounds, elements, reagents, commodities, pharmaceuticals, pollutants, and other large-scale and small-scale chemicals of interest.
Additionally, aspirin induces the formation of NO-radicals in the body, which have been shown in mice to have an independent mechanism of reducing inflammation. This reduces leukocyte adhesion, which is an important step in immune response to infection. There is currently insufficient evidence to show that aspirin helps to fight infection. [18]