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Cocaine increases alertness, feelings of well-being, euphoria, energy, sociability, and sexuality. The former are some of the desired effects of cocaine intoxication. Not having the normal use of mental faculties by reason of the introduction of cocaine is defined drug intoxication by the laws in America, Europe, and most of the rest of the World, and it is a serious crime in specific contexts ...
The insufflation of cocaine crystals may also cause physical trauma to epithelial cells, leading to inflammatory lesions, which may also worsen due to the tendency for patients to physically remove the scabs produced in the damaged tissue, which induces further mechanical damage.
Magnan's sign is a clinical sign in which people with cocaine addiction experience paraesthesia which feels like a constantly moving foreign body, such as fine sand or powder, under the skin. [ 1 ] The sign is named after Valentin Magnan .
Prenatal cocaine exposure (PCE), theorized in the 1970s, occurs when a pregnant woman uses cocaine including crack cocaine and thereby exposes her fetus to the drug.Babies whose mothers used cocaine while pregnant supposedly have increased risk of several different health issues during growth and development and are colloquially known as crack babies.
Contact high is a phenomenon that occurs in otherwise sober people who experience a drug-like effect just by coming into contact with someone who is under the influence of a psychoactive drug. In a similar way to the placebo effect, a contact high may be caused by classical conditioning as well as by the physical and social setting. [8] [9]
A two milligram dose of fentanyl powder (on pencil tip) is a lethal amount for most people. [65] In 2016, the World Health Organization estimates 34 million people used opioids and 19 million used opiates. [1] Of these, about 27 million people had opioid dependence, with the majority—but a decreasing number—using illicit heroin. [1]
This involved the exposure to highly toxic amounts of the drug due to the bursting of cocaine packets being carried within the body by "body stuffers". [38] In the same year a series of observations were made by Welti and Fishbain regarding psychosis, cardiorespiratory arrest and sudden death [39] in individuals with cocaine addiction. Since ...
Levamisole has become a common additive to illicit cocaine. It is thought to intensify the "high" by releasing dopamine in the brain, acts as a bulking agent, and is a difficult adulterant to recognize. Potential risks of levamisole-laced cocaine include neutropenia, agranulocytosis, arthralgias, retiform purpura, skin necrosis, and fever.
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