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The aims of EULAR are to reduce the burden of rheumatic diseases on the individual and society and to improve the treatment, prevention and rehabilitation of musculoskeletal diseases. It promotes the translation of research advances into daily care and fights for the recognition of the needs of people with musculoskeletal diseases by the ...
Sifalimumab is a human monoclonal antibody designed for the treatment of SLE, dermatomyositis, and polymyositis. [1] It targets interferon a. [2] Sifalimumab was developed by MedImmune; as of 2017 development had been terminated in favor of moving a competing internal product, anifrolumab, into Phase III trials. [3] [4] [5]
Department of Electricity Development (Nepali: विद्युत विकास विभाग) under Ministry of Energy, Water Resources and Irrigation is the authority to implement the government policies related to power/electricity sector. [1]
Neuropsychiatric systemic lupus erythematosus or NPSLE refers to the neurological and psychiatric manifestations of systemic lupus erythematosus. SLE is a disease in which the immune system attacks the body's own cells and tissues. It can affect various organs or systems of the body.
The Department of Local Infrastructure Development (DoLID), is a department under the Ministry of Urban Development of Nepal, responsible for assisting local governments in the engineering aspects of civil engineering construction including rural, urban and agriculture road/bridge construction and mentinance. [1] It has its branch offices. [2] [3]
Lupus nephritis is an inflammation of the kidneys caused by systemic lupus erythematosus (SLE) and childhood-onset systemic lupus erythematosus which is a more severe form of SLE that develops in children up to 18 years old; both are autoimmune diseases. [3] [4] It is a type of glomerulonephritis in which the glomeruli become inflamed.
The Nepal Super League is Nepal's first professional franchise-based football league organised by Nepal Sports and Events Management (NSEM) with technical support of ANFA. [ 1 ] [ 2 ] Seven franchises participated in the first edition of the tournament, which was held at Dasharath Rangasala Stadium from 24 April to 15 May 2021.
Epratuzumab binds to the glycoprotein CD22 of mature and malignant B-cells.. Elevated CD22 and other B-cell receptor (BCR) proteins are associated with SLE. "Epratuzumab's mechanism of action transfers these BCR proteins to helper cells called effector cells which reduces B-cell destruction and epratuzumab's impact on the body's immune system" [6] via a process called trogocytosis. [3]