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Acquired generalized lipodystrophy (AGL), also known as Lawrence syndrome [1] and Lawrence–Seip syndrome, [1] is a rare skin condition that appears during childhood or adolescence, characterized by fat loss affecting large areas of the body, particularly the face, arms, and legs.
A more specific term, lipoatrophy (from Greek lipo 'fat' and dystrophy 'abnormal or degenerative condition'), is used when describing the loss of fat from one area (usually the face). This condition is also characterized by a lack of circulating leptin which may lead to osteosclerosis .
Since 2000, IDSA has recommended against long-term antibiotic treatment for Lyme disease, finding that it is ineffective and potentially harmful. [18] [19] The American Academy of Neurology, Centers for Disease Control and Prevention, National Institutes of Health, and medical groups around the world similarly recommend against such treatment.
Lipoatrophy is the term describing the localized loss of fat tissue. This may occur as a result of subcutaneous injections of insulin in the treatment of diabetes , from the use of human growth hormone or from subcutaneous injections of copaxone used for the treatment of multiple sclerosis .
Non-progressive late-onset linear hemifacial lipoatrophy is a cutaneous condition that occurs on the malar cheek, mostly in the elderly population. [ 1 ] See also
The Greek NPHO is a private legal entity that was originally established by Law 4600 in March 2019 (as a legal entity of public law) and took its current form by Law 4633 in October 2019. It is the full successor of the former Center for Diseases Control and Prevention, which was replaced by Law 4600/2019. [4]
IDSA specifies the legal, operational, functional, and technical agreements between organisations that share data within a data space. [3] It is one of the main initiatives defining the technical specifications for data spaces in the European Union. [4] IDSA releases and maintains a reference architecture model for data spaces. [5]
Metformin is the main drug used for treatment, as it is normally used for patients with hyperglycemia. [15] Metformin reduces appetite and improves symptoms of hepatic steatosis and polycystic ovary syndrome. [4] Leptin can also be used to reverse insulin resistance and hepatic steatosis, to cause reduced food intake, and decrease blood glucose ...