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  2. Rosiglitazone - Wikipedia

    en.wikipedia.org/wiki/Rosiglitazone

    In Europe there were contraindications for use in heart failure and combination with insulin. [17] A meta analysis of all trials from 2010 and 2019 confirmed a higher risk of heart failure and a double risk when rosiglitazone was administered as add-on therapy to insulin.

  3. Management of heart failure - Wikipedia

    en.wikipedia.org/wiki/Management_of_heart_failure

    Sleep apnea is an under-recognized risk factor for heart failure. Uncontrolled sleep apnea may increase the risk of heart failure by up to 140%. [4] Weight reduction – through physical activity and dietary modification, as obesity is a risk factor for heart failure and left ventricular hypertrophy. Effective weight management has been shown ...

  4. Bidirectional Glenn procedure - Wikipedia

    en.wikipedia.org/wiki/Bidirectional_Glenn_procedure

    The mechanism of many of the risks and complications related to failure of the Glenn bidirectional shunt is thought to be thrombosis. Right-side dominant circulation, elevated pulmonary vascular resistance, and prolonged operative and recovery time are the major factors that increase the risk of complications and failure.

  5. Aortic regurgitation - Wikipedia

    en.wikipedia.org/wiki/Aortic_regurgitation

    Aortic regurgitation (AR), also known as aortic insufficiency (AI), is the leaking of the aortic valve of the heart that causes blood to flow in the reverse direction during ventricular diastole, from the aorta into the left ventricle.

  6. Heart failure - Wikipedia

    en.wikipedia.org/wiki/Heart_failure

    Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to fill with and pump blood.. Although symptoms vary based on which side of the heart is affected, HF typically presents with shortness of breath, excessive fatigue, and bilateral leg swelling. [3]

  7. Levosimendan - Wikipedia

    en.wikipedia.org/wiki/Levosimendan

    Levosimendan / ˌ l iː v oʊ s aɪ ˈ m ɛ n d ən / is a calcium sensitizer used in the management of acutely decompensated congestive heart failure. It is marketed under the trade name Simdax (Orion Corporation). Overall the drug has a two fold mechanism of action.

  8. Acute decompensated heart failure - Wikipedia

    en.wikipedia.org/wiki/Acute_decompensated_heart...

    Acute decompensated heart failure (ADHF) is a sudden worsening of the signs and symptoms of heart failure, which typically includes difficulty breathing , leg or feet swelling, and fatigue. [1] ADHF is a common and potentially serious cause of acute respiratory distress. The condition is caused by severe congestion of multiple organs by fluid ...

  9. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    Heart failure - Giving 2.5 times of previous oral dose twice daily for those with acute decompensated heart failure is a reasonable strategy. However, daily assessment of clinical response is needed to adjust the subsequent doses. [6] Edema - Volume overload associated with liver cirrhosis, heart failure, or nephrotic syndrome [11]

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