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This is an accepted version of this page This is the latest accepted revision, reviewed on 22 February 2025. DNA molecule containing genetic material of a cell This article is about the DNA molecule. For the genetic algorithm, see Chromosome (genetic algorithm). Chromosome (10 7 - 10 10 bp) DNA Gene (10 3 - 10 6 bp) Function A chromosome and its packaged long strand of DNA unraveled. The DNA's ...
A diagram of the mitotic phases. Mitosis is the process by which a eukaryotic cell separates the chromosomes in its cell nucleus into two identical sets in two nuclei. [8] During the process of mitosis the pairs of chromosomes condense and attach to microtubules that pull the sister chromatids to opposite sides of the cell. [9]
Commonly, many people think the structure of a chromosome is in an "X" shape. But this is only present when the cell divides. Researchers have now been able to model the structure of chromosomes when they are active. This is extremely important because the way that DNA folds up in chromosome structures is linked to the way DNA is used.
Before typical cell division, these chromosomes are duplicated in the process of DNA replication, providing a complete set of chromosomes for each daughter cell. Eukaryotic organisms ( animals , plants , fungi and protists ) store most of their DNA inside the cell nucleus as nuclear DNA , and some in the mitochondria as mitochondrial DNA or in ...
In eukaryotes, the cell cycle consists of four main stages: G 1, during which a cell is metabolically active and continuously grows; S phase, during which DNA replication takes place; G 2, during which cell growth continues and the cell synthesizes various proteins in preparation for division; and the M phase, during which the duplicated ...
The structure of the condensed chromatin is thought to be loops of 30 nm fibre to a central scaffold of proteins. It is, however, not well-characterised. Chromosome scaffolds play an important role to hold the chromatin into compact chromosomes. Loops of 30 nm structure further condense with scaffold, into higher order structures. [21]
The organization of chromosomes into distinct regions within the nucleus was first proposed in 1885 by Carl Rabl.Later in 1909, with the help of the microscopy technology at the time, Theodor Boveri coined the termed chromosome territories after observing that chromosomes occupy individually distinct nuclear regions. [6]
The solenoid structure's most obvious function is to help package the DNA so that it is small enough to fit into the nucleus. This is a big task as the nucleus of a mammalian cell has a diameter of approximately 6 μm, whilst the DNA in one human cell would stretch to just over 2 metres long if it were unwound. [6]