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Sildenafil is most commonly prescribed to be taken one time per day in doses between 25 and 100 mg for ED. Your healthcare provider will determine the best dosage for you based on a number of factors.
According to the Food and Drug Administration (FDA), it usually takes 30 to 60 minutes for Viagra or generic sildenafil to start producing a noticeable improvement in your climax quality.
Studies have shown a 70 to 80 percent success rate in patients who use this treatment. ... Sildenafil can still be used to treat hypertension, but today, the primary use of this PDE5 inhibitor is ...
Chemical structure of sildenafil (Viagra), the prototypical PDE5 inhibitor. A phosphodiesterase type 5 inhibitor (PDE5 inhibitor) is a vasodilating drug that works by blocking the degradative action of cGMP-specific phosphodiesterase type 5 (PDE5) on cyclic GMP in the smooth muscle cells lining the blood vessels supplying various tissues.
This metabolite also has an affinity for the PDE receptors, about 40% of that of sildenafil. Thus, the metabolite is responsible for about 20% of sildenafil's action. Sildenafil is excreted as metabolites predominantly in the feces (about 80% of administered oral dose) and to a lesser extent in the urine (around 13% of the administered oral dose).
Viagra is the brand-name version of a medication called sildenafil citrate. It belongs to a class of drugs called phosphodiesterase 5 inhibitors, more commonly known as PDE5 inhibitors.
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