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Spironolactone is an acne treatment prescribed by dermatologists. Find out how spironolactone improves the appearance of hormonal acne, side effects, and more. Everything I Wish I Knew About ...
Spironolactone may be more effective than birth control pills in the treatment of acne, and the combination of spironolactone with a birth control pill may have greater effectiveness for acne than either alone. [85] In addition, some clinical research has found that flutamide is more effective than spironolactone in the treatment of acne. [64]
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Overview. Acne is a skin condition characterized by clogged pores. When pores get clogged, it causes red lesions — which you know as pimples — to form on the face or other areas of the body ...
Spirolactones are a class of functional group in organic chemistry featuring a cyclic ester attached spiro to another ring system. The name is also used to refer to a class of synthetic steroids, called steroid-17α-spirolactones, 17α-spirolactosteroids, or simply 17α-spirolactones, which feature their spirolactone group at the C17α position.
Hyperandrogenism is a medical condition characterized by high levels of androgens.It is more common in women than men. [4] Symptoms of hyperandrogenism may include acne, seborrhea, hair loss on the scalp, increased body or facial hair, and infrequent or absent menstruation.
According to a study in JAMA Dermatology, the prescribing rates of spironolactone for acne in women rose about 300% from 2017 to 2020.
Side effects of spironolactone in clinical studies for acne in women Side effect RCTs Tooltip Randomized controlled trials (n (ITT Tooltip Intention-to-treat analysis) = 326) Case series (n (ITT Tooltip Intention-to-treat analysis) = 663) Number % Number % Menstrual irregularities: 38: 13.4 (of 283) 216: 33.4 (of 646) Breast tenderness: 8: 2.5: ...