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Production of antibiotics is a naturally occurring event, that thanks to advances in science can now be replicated and improved upon in laboratory settings. Due to the discovery of penicillin by Alexander Fleming, and the efforts of Florey and Chain in 1938, large-scale, pharmaceutical production of antibiotics has been made possible.
The Journal of Antibiotics is a peer-reviewed medical journal published by the Nature Publishing Group for the Japan Antibiotics Research Association.. The journal seeks to endorse studies on antibiotics and associated types of biologically-active substances.
Drug delivery systems have been around for many years, but there are a few recent applications of drug delivery that warrant 1. Drug delivery to the brain: Many drugs can be harmful when administered systemically; the brain is very sensitive to medications and can easily cause damage if a drug is administered directly into the bloodstream.
This is when the development of "smart drug delivery" originated. Encapsulated within the idea of smart drug delivery is the use of gated delivery systems. Researchers discovered that certain materials could be loaded and capped to prevent premature drug release. The caps could subsequently be removed using different external stimuli.
Their targeting ability was believed to limit side effects for cancer patients and to give a wider therapeutic window than other chemotherapeutic agents, although this promise hasn't yet been realized in the clinic. [7] ADC technologies have been featured in many publications, [8] [9] including scientific journals.
Specimens are collected from affected body sites, preferably before antibiotics are given. For example, a person in an intensive care unit may develop a hospital-acquired pneumonia . There is a chance the causal bacteria, or its sensitivity to antibiotics, may be different to community-acquired pneumonia . [ 2 ]
Expert Opinion on Drug Delivery is a monthly peer-reviewed medical journal publishing review articles covering all aspects of research on drug delivery, from initial concept to potential therapeutic application and final relevance in clinical use. It was established in 2004 and is published by Taylor and Francis Group.
[74] [77] [78] As a therapeutic, siRNA is able to be delivered locally, through the eye or nose, to treat various diseases. [5] Local delivery benefits from simple formulation and drug delivery and high bioavailability of the drug. [5] Systemic delivery is necessary to target cancers and other diseases. [5]