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It is the calcium salt of citric acid and malic acid with variable composition. Calcium citrate malate's bioavailability stems from its water-solubility and its method of dissolution. When dissolved, it releases calcium ions and a calcium citrate complex. Calcium citrate malate is similar to calcium malate and other calcium salts.
Calcium supplements, unlike calcium from dietary sources, appear to increase the risk of kidney stones. [1] Adults generally require about a gram of calcium a day. [1] Calcium is particularly important for bones, muscles, and nerves. [1] The medical use of calcium supplements began in the 19th century. [5]
ATC code A12 Mineral supplements is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Calcium citrate is the calcium salt of citric acid. It is commonly used as a food additive , usually as a preservative, but sometimes for flavor. In this sense, it is similar to sodium citrate. Calcium citrate is also found in some dietary calcium supplements (e.g. Citracal or Caltrate). Calcium makes up 24.1% of calcium citrate (anhydrous) and ...
Calcium is a common constituent of multivitamin dietary supplements, [8] but the composition of calcium complexes in supplements may affect its bioavailability which varies by solubility of the salt involved: calcium citrate, malate, and lactate are highly bioavailable, while the oxalate is less.
Osteomalacia is a disease characterized by the softening of the bones caused by impaired bone metabolism primarily due to inadequate levels of available phosphate, calcium, and vitamin D, or because of resorption of calcium. The impairment of bone metabolism causes inadequate bone mineralization.
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