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20714 Ensembl ENSG00000196136 ENSMUSG00000058207 UniProt P01011 P07759 RefSeq (mRNA) NM_001085 NM_011458 RefSeq (protein) NP_001076 NP_035588 Location (UCSC) Chr 14: 94.61 – 94.62 Mb Chr 12: 104.3 – 104.31 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Alpha 1-antichymotrypsin (symbol α 1 AC, A1AC, or a1ACT) is an alpha globulin glycoprotein that is a member of the serpin ...
Alpha-1 antitrypsin or α 1-antitrypsin (A1AT, α 1 AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the SERPINA1 gene . A protease inhibitor , it is also known as alpha 1 –proteinase inhibitor ( A1PI ) or alpha 1 -antiproteinase ( A1AP ) because it inhibits various proteases (not just trypsin ). [ 5 ]
Orosomucoid (ORM) or alpha-1-acid glycoprotein (α 1 AGp, [1] AGP or AAG) is an acute phase protein found in plasma. It is an alpha-globulin glycoprotein and is modulated by two polymorphic genes. It is synthesized primarily in hepatocytes and has a normal plasma concentration between 0.6–1.2 mg/mL (1–3% plasma protein). [ 2 ]
In blood test results, the IEF results are notated as, e.g., PiMM, where Pi stands for protease inhibitor and "MM" is the banding pattern of that person. [citation needed] Other detection methods include use of enzyme-linked-immuno-sorbent-assays in vitro and radial immunodiffusion. Alpha-1 antitrypsin levels in the blood depend on the genotype.
Schematic representation of a protein electrophoresis gel. Alpha globulins are a group of globular proteins in plasma [1] that are highly mobile in alkaline or electrically charged solutions. They inhibit certain blood proteases and show significant inhibitor activity. The alpha globulins typically have molecular weights of around 93 kDa.
15160 Ensembl ENSG00000099937 ENSMUSG00000022766 UniProt P05546 P49182 RefSeq (mRNA) NM_000185 NM_008223 NM_001331047 RefSeq (protein) NP_000176 NP_001317976 NP_032249 Location (UCSC) Chr 22: 20.77 – 20.79 Mb Chr 16: 17.15 – 17.16 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Heparin cofactor II (HCII), a protein encoded by the SERPIND1 gene, is a coagulation factor that ...
Positive acute-phase proteins serve (as part of the innate immune system) different physiological functions within the immune system.Some act to destroy or inhibit growth of microbes, e.g., C-reactive protein, mannose-binding protein, [3] complement factors, ferritin, ceruloplasmin, serum amyloid A and haptoglobin.
12401 Ensembl ENSG00000277405 ENSG00000170099 ENSMUSG00000060807 UniProt P08185 Q06770 RefSeq (mRNA) NM_001756 NM_007618 RefSeq (protein) NP_001747 NP_031644 Location (UCSC) Chr 14: 94.3 – 94.32 Mb Chr 12: 103.61 – 103.62 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transcortin, also known as corticosteroid-binding globulin (CBG) or serpin A6, is a protein produced in the ...
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