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An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as athlete's foot, ringworm, candidiasis (thrush), serious systemic infections such as cryptococcal meningitis, and others. Such drugs are usually obtained by a doctor's prescription, but a few ...
Caspofungin (INN; [1] [4] brand name Cancidas) is a lipopeptide antifungal drug from Merck & Co., Inc.. [5] It is a member of a class of antifungals termed the echinocandins. [medical citation needed] It works by inhibiting the enzyme (1→3)-β-D-glucan synthase and thereby disturbing the integrity of the fungal cell wall.
Fluconazole is a first-generation triazole antifungal medication. It differs from earlier azole antifungals (such as ketoconazole) in that its structure contains a triazole ring instead of an imidazole ring. While the imidazole antifungals are mainly used topically, fluconazole and certain other triazole antifungals are preferred when systemic ...
Terbinafine is an antifungal medication used to treat pityriasis versicolor, fungal nail infections, and ringworm including jock itch and athlete's foot. [1][2][3] It is either taken by mouth or applied to the skin as a cream or ointment. [1][4] The cream and ointment should not be used for fungal nail infections. [5]
Amphotericin B is an antifungal medication used for serious fungal infections and leishmaniasis. [3] The fungal infections it is used to treat include mucormycosis, aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis. [4] For certain infections it is given with flucytosine. [5]
References. Topical antifungal. Topical antifungaldrugs are used to treat fungal infections on the skin, scalp, nails, vagina or inside the mouth. These medications come as creams, gels, lotions, ointments, powders, shampoos, tinctures and sprays. Most antifungal drugs induce fungal cell death by destroying the cell wall of the fungus.
Echinocandins are a class of antifungal drugs [ 1 ] that inhibit the synthesis of β-glucan in the fungal cell wall via noncompetitive inhibition of the enzyme 1,3-β glucan synthase. [ 2 ][ 3 ] The class has been dubbed the " penicillin of antifungals," [ 4 ] along with the related papulacandins, as their mechanism of action resembles that of ...
Ibrexafungerp was approved for medical use in the United States in June 2021. [1] [4] It is the first non-azole oral antifungal drug to be approved by the U.S. Food and Drug Administration (FDA) for the treatment of vaginal yeast infections. [4] The FDA considers it to be a first-in-class medication. [5]