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An interesting off-label indication of pentoxifylline is the supportive treatment of distal diabetic neuropathy, where it can be added, for example, to thioctic acid or gabapentin. [17] Theoretically, it can (among other things) act prophylactically against ulcerative changes of the lower limbs associated with chronically decompensated diabetes.
7-Methylxanthine (7-MX), also known as heteroxanthine, is an active metabolite of caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine). [ 1 ] [ 2 ] It is a non-selective antagonist of the adenosine receptors .
Xanthine (/ ˈ z æ n θ iː n / or / ˈ z æ n θ aɪ n /, from Ancient Greek ξανθός xanthós ' yellow ' for its yellowish-white appearance; archaically xanthic acid; systematic name 3,7-dihydropurine-2,6-dione) is a purine base found in most human body tissues and fluids, as well as in other organisms. [2]
Acute pain is something more than 80 million Americans fill prescriptions to treat each year, according to Vertex. As opposed to chronic pain, which can last well after an injury or illness has ...
Organized research began after World War II with the recognition of E. coli III as a source and cause of epidemic diarrhea, and the development of a treatment for histoplasmosis. In 2009, among free-standing children's hospitals, The Research Institute ranked 9th based on NIH funding and amongst all other pediatric research organizations ranked ...
The characteristic signals, distinguishing theophylline from related methylxanthines, are approximately 3.23δ and 3.41δ, corresponding to the unique methylation possessed by theophylline. The remaining proton signal, at 8.01δ, corresponds to the proton on the imidazole ring, not transferred between the nitrogen.
The veteran was diagnosed with necrotizing fasciitis, a rare infection with bacteria that can cause “flesh-eating disease,” the CDC notes. Even with treatment, up to 20% of patients die ...
The expanded maternity unit is designed to handle 3,500 deliveries a year. The expansion of the heart center included two operating rooms and many cardiology upgrades allowing it to function as a fully functioning emergency cardiac treatment center. Following this, in July 2003, an $18 million project to expand the emergency room was completed. [9]
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