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  2. Cocaine intoxication - Wikipedia

    en.wikipedia.org/wiki/Cocaine_intoxication

    Cocaine increases alertness, feelings of well-being, euphoria, energy, sociability, and sexuality. The former are some of the desired effects of cocaine intoxication. Not having the normal use of mental faculties by reason of the introduction of cocaine is defined drug intoxication by the laws in America, Europe, and most of the rest of the World, and it is a serious crime in specific contexts ...

  3. Cocaine dependence - Wikipedia

    en.wikipedia.org/wiki/Cocaine_dependence

    Cocaine dependence is a neurological disorder that is characterized by withdrawal symptoms upon cessation from cocaine use. [1] It also often coincides with cocaine addiction which is a biopsychosocial disorder characterized by persistent use of cocaine and/or crack despite substantial harm and adverse consequences.

  4. Cocaine - Wikipedia

    en.wikipedia.org/wiki/Cocaine

    Cocaine (from French cocaïne, from Spanish coca, ultimately from Quechua kúka) [13] is a tropane alkaloid that acts as a central nervous system stimulant.As an extract, it is mainly used recreationally and often illegally for its euphoric and rewarding effects.

  5. Epigenetics of cocaine addiction - Wikipedia

    en.wikipedia.org/wiki/Epigenetics_of_cocaine...

    Cocaine addiction is the compulsive use of cocaine despite adverse consequences. It arises through epigenetic modification (e.g., through HDAC , sirtuin , and G9a ) and transcriptional regulation (primarily through ΔFosB 's AP-1 complex ) of genes in the nucleus accumbens .

  6. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...

  7. Crack cocaine - Wikipedia

    en.wikipedia.org/wiki/Crack_cocaine

    Two grams of crack cocaine. Crack cocaine, commonly known simply as crack, and also known as rock, is a free base form of the stimulant cocaine that can be smoked. Crack offers a short, intense high to smokers. The Manual of Adolescent Substance Abuse Treatment calls it the most addictive form of cocaine. [1]

  8. Cocaine in the United States - Wikipedia

    en.wikipedia.org/wiki/Cocaine_in_the_United_States

    The National Household Survey on Drug Abuse (NHSDA) reported that in the United States in 1999 that cocaine was used by 3.7 million people, or 1.7% of the household population age 12 and older. Estimates of the current number of those who use cocaine regularly (at least once per month) vary, but 1.5 million is a widely accepted figure within ...

  9. Prenatal cocaine exposure - Wikipedia

    en.wikipedia.org/wiki/Prenatal_cocaine_exposure

    Prenatal cocaine exposure (PCE), theorized in the 1970s, occurs when a pregnant woman uses cocaine including crack cocaine and thereby exposes her fetus to the drug.Babies whose mothers used cocaine while pregnant supposedly have increased risk of several different health issues during growth and development and are colloquially known as crack babies.

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