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Oxygenation zones are numbered inside the diamond-shaped acinus (in red). Zone three is closest to the central vein and zone one is closest to the portal triad. Zones differ by function: zone I hepatocytes are specialized for oxidative liver functions such as gluconeogenesis, β-oxidation of fatty acids and cholesterol synthesis
The hepatic artery provides 30 to 40% of the oxygen to the liver, while only accounting for 25% of the total liver blood flow. The rest comes from the partially deoxygenated blood from the portal vein. The liver consumes about 20% of the total body oxygen when at rest.
A liver segment is one of eight segments of the liver as described in the widely used Couinaud classification (named after Claude Couinaud) in the anatomy of the liver. This system divides the lobes of the liver into eight segments based on a transverse plane through the bifurcation of the main portal vein , [ 1 ] arranged in a clockwise manner ...
The asymmetry within the abdominal cavity, caused by the position of the liver, typically results in the right kidney being slightly lower and smaller than the left, and being placed slightly more to the middle than the left kidney. [10] [11] [12] The left kidney is approximately at the vertebral level T12 to L3, [13] and the right is slightly ...
Measuring approximately 8 cm (3 inches) long in adults, [3] the portal vein is located in the right upper quadrant of the abdomen, originating behind the neck of the pancreas. [ 4 ] In most individuals, the portal vein is formed by the union of the superior mesenteric vein and the splenic vein . [ 5 ]
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The gallbladder is located on the undersurface of the right lobe of the liver. [9] It produces bile, which is used to help process fats in the body. [9] Humans can live without the gallbladder. [10] The largest lymphatic organ is the spleen, which is dark purple and located under the lower ribs, around the left side of the upper abdomen.
A liver sinusoid is a type of capillary known as a sinusoidal capillary, discontinuous capillary or sinusoid, that is similar to a fenestrated capillary, having discontinuous endothelium that serves as a location for mixing of the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein.