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  2. Neurogenic claudication - Wikipedia

    en.wikipedia.org/wiki/Neurogenic_claudication

    Neurogenic claudication commonly describes pain, weakness, fatigue, tingling, heaviness and paresthesias that extend into the lower extremities. [9] These symptoms may involve only one leg, but they usually involve both. Leg pain is usually more significant than back pain in individuals who have both. [12]

  3. Thyrotoxic myopathy - Wikipedia

    en.wikipedia.org/wiki/Thyrotoxic_myopathy

    Other research indicates muscle fiber fatigue, weakness, and degradation associated with TM is the direct action thyroxine has on the muscle fibers themselves. Research suggests thyroxine directly causes a decrease in protein kinase affinity to cAMP within muscle fibers [ 1 ] [ 10 ] This causes an increase in cAMP within the muscle fibers since ...

  4. Inclusion body myositis - Wikipedia

    en.wikipedia.org/wiki/Inclusion_body_myositis

    Weakness comes on slowly (over months to years) in an asymmetric manner and progresses steadily, leading to severe weakness and wasting of arm and leg muscles. IBM is more common in men than women. [10] Patients may become unable to perform activities of daily living and most require assistive devices within 5 to 10 years of symptom onset.

  5. Frailty syndrome - Wikipedia

    en.wikipedia.org/wiki/Frailty_syndrome

    Frailty or frailty syndrome refers to a state of health in which older adults gradually lose their bodies' in-built reserves and functioning. This makes them more vulnerable, less able to recover and even apparently minor events (infections, environmental changes) can have drastic impacts on their physical and mental health.

  6. Camptocormia - Wikipedia

    en.wikipedia.org/wiki/Camptocormia

    Idiopathic primary BSS is a late-onset myopathy with progressive muscular weakness that is detected on the spinal extensor muscles in elderly patients and is more predominant in females. [2] The pathogenesis of primary BSS is typically related to fibrosis and fatty infiltration of muscular tissues and to mitochondrial changes due to the aging ...

  7. Neuromuscular disease - Wikipedia

    en.wikipedia.org/wiki/Neuromuscular_disease

    Further causes of neuromuscular diseases are: Polymyositis. Inflammatory muscle disorders. Polymyalgia rheumatica (or "muscle rheumatism") is an inflammatory condition that mainly occurs in the elderly; it is associated with giant-cell arteritis (It often responds to prednisolone). [18] Polymyositis is an autoimmune condition in which the ...

  8. Muscle weakness - Wikipedia

    en.wikipedia.org/wiki/Muscle_weakness

    Muscle weakness is a lack of muscle strength. Its causes are many and can be divided into conditions that have either true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy.

  9. Lumbar spinal stenosis - Wikipedia

    en.wikipedia.org/wiki/Lumbar_spinal_stenosis

    These symptoms include pain, weakness, and tingling of the legs, [5] which may radiate down the legs to the feet. [6] Additional symptoms in the legs may be fatigue, heaviness, weakness, a sensation of tingling, pricking, or numbness , and leg cramps, as well as bladder symptoms. [ 6 ]

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