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Terconazole is an antifungal drug used to treat vaginal yeast infection. It comes as a lotion or a suppository and disrupts the biosynthesis of fats in a yeast cell. It has a relatively broad spectrum compared to azole compounds but not triazole compounds.
Topical antifungal drugs are used to treat fungal infections on the skin, scalp, nails, vagina or inside the mouth. These medications come as creams, gels, lotions, ointments, powders, shampoos, tinctures and sprays. Most antifungal drugs induce fungal cell death by destroying the cell wall of the fungus.
The number of cases of vaginal yeast infection is not entirely clear because it is not a reportable disease and it is commonly diagnosed clinically without laboratory confirmation. [ 37 ] Candidiasis is one of the three most common vaginal infections along with bacterial vaginosis and trichomonas . [ 3 ]
Oral candidiasis is the most common fungal infection of the mouth, [77] and it also represents the most common opportunistic oral infection in humans. [78] Infections of the mouth occur in about 6% of babies less than a month old. [7] About 20% of those receiving chemotherapy for cancer and 20% of those with AIDS also develop the disease. [7]
Fluconazole was patented in 1981 and came into commercial use in 1988. [7] It is on the World Health Organization's List of Essential Medicines. [8] Fluconazole is available as a generic medication. [5] In 2022, it was the 160th most commonly prescribed medication in the United States, with more than 3 million prescriptions. [9] [10]
Yeast infections: Local azole, in the form of ovula and cream. All agents appear to be equally effective. [33] These anti-fungal medications, which are available in over the counter form, are generally used to treat yeast infections. Treatment may last anywhere between one, three, or seven days. [21]
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