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  2. Allele - Wikipedia

    en.wikipedia.org/wiki/Allele

    An allele [1], or allelomorph, is a variant of the sequence of nucleotides at a particular location, or locus, on a DNA molecule. [2]Alleles can differ at a single position through single nucleotide polymorphisms (SNP), [3] but they can also have insertions and deletions of up to several thousand base pairs.

  3. Non-Mendelian inheritance - Wikipedia

    en.wikipedia.org/wiki/Non-Mendelian_inheritance

    These laws describe the inheritance of traits linked to single genes on chromosomes in the nucleus. In Mendelian inheritance , each parent contributes one of two possible alleles for a trait. If the genotypes of both parents in a genetic cross are known, Mendel's laws can be used to determine the distribution of phenotypes expected for the ...

  4. Coalescent theory - Wikipedia

    en.wikipedia.org/wiki/Coalescent_theory

    Coalescent theory is a model of how alleles sampled from a population may have originated from a common ancestor.In the simplest case, coalescent theory assumes no recombination, no natural selection, and no gene flow or population structure, meaning that each variant is equally likely to have been passed from one generation to the next.

  5. Locus (genetics) - Wikipedia

    en.wikipedia.org/wiki/Locus_(genetics)

    In genetics, a locus (pl.: loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located. [1] Each chromosome carries many genes, with each gene occupying a different position or locus; in humans, the total number of protein-coding genes in a complete haploid set of 23 chromosomes is estimated at ...

  6. Zygosity - Wikipedia

    en.wikipedia.org/wiki/Zygosity

    The words homozygous, heterozygous, and hemizygous are used to describe the genotype of a diploid organism at a single locus on the DNA. Homozygous describes a genotype consisting of two identical alleles at a given locus, heterozygous describes a genotype consisting of two different alleles at a locus, hemizygous describes a genotype consisting of only a single copy of a particular gene in an ...

  7. Genetic linkage - Wikipedia

    en.wikipedia.org/wiki/Genetic_linkage

    Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction.Two genetic markers that are physically near to each other are unlikely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be more linked than markers that are far apart.

  8. Haplotype - Wikipedia

    en.wikipedia.org/wiki/Haplotype

    Normally these organisms have their DNA organized in two sets of pairwise similar chromosomes. The offspring gets one chromosome in each pair from each parent. A set of pairs of chromosomes is called diploid and a set of only one half of each pair is called haploid. The haploid genotype (haplotype) is a genotype that considers the singular ...

  9. Multilocus genotype - Wikipedia

    en.wikipedia.org/wiki/Multilocus_genotype

    A multilocus genotype is the combination of alleles found at two or more loci in a single individual. For example, in a diploid species, if there are two SNP loci and the first locus has alleles A and G, while the second locus has alleles T and C, the multilocus genotype can be represented as {A/G,T/C}. If the genome is not haploid then the ...