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The plasma half-life is about 35 to 40 hours when carbamazepine is given as single dose, but it is a strong inducer of liver enzymes, and the plasma half-life shortens to about 12 to 17 hours when it is given repeatedly. The half-life can be further shortened to 9–10 hours by other enzyme inducers such as phenytoin or phenobarbital. About 70% ...
10 mg ~25%: 2–4 3:1 30 min 3–6 hours ... [25] 3–4 2.5–3.33 mg (60–87 / ±75% PO) / 78.2% [23] ... 0.83–10 μg (20–40 μg SL) Carfentanil [42]
This is a list of psychiatric medications used by psychiatrists and other physicians to treat mental illness or distress. The list is ordered alphabetically according to the condition or conditions, then by the generic name of each medication. The list is not exhaustive and not all drugs are used regularly in all countries.
A derivative of carbamazepine that has similar efficacy and is better tolerated and is also available generically. Eslicarbazepine acetate (2009). Photoswitchable analogues of carbamazepine (2024) are research compounds developed to control its pharmacological activity locally and on demand using light, with the purpose to reduce adverse ...
Tegretol (carbamazepine) – an anticonvulsant used as a mood stabilizer; Trilafon (perphenazine)- an antipsychotic used to treat schizophrenia; Tranxene, Novo-Clopate (clorazepate) – a benzodiazepine with anxiolytic, anticonvulsant, sedative, hypnotic, and skeletal muscle relaxant properties
The weight loss drug Zepbound, generically known as tirzepatide, is also now an approved medication to treat obstructive sleep apnea, per a Food and Drug Administration Dec. 20 press release.
Felbamate interacts with several other AEDs, including phenytoin, valproate, and carbamazepine; dosage adjustments may be necessary to avoid adverse effects. Concomitant administration of felbamate and carbamazepine decreases blood levels of both drugs, while increasing the level of carbamazepine-10,11 epoxide, the active metabolite of ...
In the United States, cenobamate is indicated for the treatment of partial-onset seizures in adults. [3]In the European Union, it is indicated for the adjunctive treatment of focal-onset seizures with or without secondary generalization in adults with epilepsy who have not been adequately controlled despite a history of treatment with at least two anti-epileptic medications.